ArticleSurgical case reports2020
Rapidly progressed neuroendocrine carcinoma in the extrahepatic bile duct: a case report and review of the literature.
Article in Surgical case reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 8 citations in OpenAlex.
- Transient response to cisplatin-etoposide chemotherapy for early postoperative recurrence of large cell neuroendocrine carcinoma of the distal bile duct: a case report.Clinical journal of gastroenterology · 2026Article
- Article
- Neuroendocrine carcinoma of the common hepatic duct coexisting with distal cholangiocarcinoma: A case report and review of literature.World journal of gastrointestinal surgery · 2024Article
- Neuroendocrine Carcinoma of the Extrahepatic Bile Ducts: A Case Report.The American journal of case reports · 2023Article
- Primary extrahepatic biliary neuroendocrine tumor: a case report.Journal of surgical case reports · 2023Article
- Small-cell Neuroendocrine Carcinoma of the Extrahepatic Bile Duct: A Rare Case Report.The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2023Review
- Case of resected small-cell neuroendocrine carcinoma of the extrahepatic bile duct.Journal of surgical case reports · 2022Article
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Authors and funding
15 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNeuroendocrine carcinoma (NEC) originating from the extrahepatic bile duct (EHBD) is very rare but is known for its aggressiveness and poor prognosis. We herein report a case of rapidly progressed NEC in the extrahepatic bile duct. CASE PRESENTATION: An 84-year-old man was referred to our facility with obstructive jaundice and abdominal pain. Imaging studies revealed an irregular filling defect in the middle bile duct by endoscopic retrograde cholangiopancreatography and an enhanced wall thickening from the middle to distal portion by enhanced computed tomography. The patient was initially diagnosed with extrahepatic cholangiocarcinoma by a bile duct biopsy and underwent pancreatoduodenectomy with lymph node dissection. The pathological findings showed an NEC with an adenosquamous carcinoma component in the extrahepatic bile duct with lymph node metastases. The patient experienced multiple liver metastases 1 month after surgery and died 3 months after surgery. Due to the rapid progression of his disease, his general condition deteriorated, and he was unable to receive any additional treatments, such as chemotherapy.
conclusionAs shown in our case, NEC of the EHBD has an extremely poor prognosis and can sometimes progress rapidly. Multimodality treatment should be considered, even in cases of locoregional disease.
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