Evidence map›Paper›PMID 32747834›Full record

ArticleNature biomedical engineering2020

Power-saving design opportunities for wireless intracortical brain-computer interfaces.

Nir Even-Chen, Dante G Muratore, Sergey D Stavisky, Leigh R Hochberg, Jaimie M Henderson, Boris Murmann, Krishna V Shenoy

Abstract read
In one paragraph

Article in Nature biomedical engineering, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Review
  2. Article
  3. A Framework for Compressive On-Chip Action Potential Recording.IEEE transactions on bio-medical engineering · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. In vivo microelectrode arrays for neuroscience.Nature reviews. Methods primers · 2025
    Article
  8. Review
  9. Non-Invasive Brain-Computer Interfaces: State of the Art and Trends.IEEE reviews in biomedical engineering · 2025
    Review
  10. Article
  11. Article
  12. A 1024-Channel 268 nW/pixel 36×36IEEE journal of solid-state circuits · 2024
    Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. A brain-computer typing interface using finger movements.International IEEE/EMBS Conference on Neural Engineering : [proceedings]. International IEEE EMBS Conference on Neural Engineering · 2023
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Nir Even-Chen *Department of Electrical Engineering, Stanford University, Stanford, CA, USA. nirec@stanford.edu.ORCID http://orcid.org/0000-0003-2186-5567
Dante G Muratore *Department of Electrical Engineering, Stanford University, Stanford, CA, USA.ORCID http://orcid.org/0000-0001-5062-0353
Sergey D StaviskyDepartment of Electrical Engineering, Stanford University, Stanford, CA, USA.ORCID http://orcid.org/0000-0002-5238-0573
Leigh R HochbergDepartment of Veterans Affairs Medical Center, Center for Neurorestoration and Neurotechnology, Providence, RI, USA.ORCID http://orcid.org/0000-0003-0261-2273
Jaimie M HendersonWu Tsai Neurosciences Institute, Stanford University, Stanford, CA, USA.ORCID http://orcid.org/0000-0002-3276-2267
Boris MurmannDepartment of Electrical Engineering, Stanford University, Stanford, CA, USA.ORCID http://orcid.org/0000-0003-3417-8782
Krishna V ShenoyDepartment of Electrical Engineering, Stanford University, Stanford, CA, USA.ORCID http://orcid.org/0000-0003-1534-9240

Funding

Engaging new cognitive and motor signals to improve communication prosthesesR01DC014034 · NIDCD · STANFORD UNIVERSITY · PI JAIMIE M HENDERSON · 2015 to 2026
$8.2M
Restoring Communication with an Intracortical Neural Interface SystemR01DC009899 · NIDCD · MASSACHUSETTS GENERAL HOSPITAL · PI HOCHBERG, LEIGH R · 2009 to 2017
$7.0M
Understanding the Neural Basis of Volitional State through Continuous Recordings in HumansU01NS098968 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI CASH, SYDNEY S · 2016 to 2018
$4.7M
High-Bandwidth Wireless Interfaces for Continuous Human Intracortical RecordingUH2NS095548 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI HOCHBERG, LEIGH R, NURMIKKO, ARTO · 2015 to 2019
$3.7M
Toward an Animal Model of Freely Moving HumanDP1HD075623 · NICHD · STANFORD UNIVERSITY · PI SHENOY, KRISHNA V · 2012 to 2013
$1.6M
Howard Hughes Medical InstituteNICHD NIH HHS DP1 HD075623NIDCD NIH HHS R01 DC009899NIDCD NIH HHS R01 DC014034NINDS NIH HHS U01 NS098968NINDS NIH HHS UH2 NS095548RRD VA I01 RX002295RRD VA I50 RX002864
6 · The paper itself

Abstract

The efficacy of wireless intracortical brain-computer interfaces (iBCIs) is limited in part by the number of recording channels, which is constrained by the power budget of the implantable system. Designing wireless iBCIs that provide the high-quality recordings of today's wired neural interfaces may lead to inadvertent over-design at the expense of power consumption and scalability. Here, we report analyses of neural signals collected from experimental iBCI measurements in rhesus macaques and from a clinical-trial participant with implanted 96-channel Utah multielectrode arrays to understand the trade-offs between signal quality and decoder performance. Moreover, we propose an efficient hardware design for clinically viable iBCIs, and suggest that the circuit design parameters of current recording iBCIs can be relaxed considerably without loss of performance. The proposed design may allow for an order-of-magnitude power savings and lead to clinically viable iBCIs with a higher channel count.

Indexed as

Brain-Computer InterfacesAnimalsElectric Power SuppliesElectrodes, ImplantedEquipment DesignHandHumansMacaca mulattaMaleMiddle AgedWireless Technology

Identifiers

PMID32747834
PMCPMC8286886

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.