ArticleNature medicine2020
Single-cell atlas of colonic CD8
Abstract read
In one paragraph
Article in Nature medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 151 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
151citing papers in PubMed, 1 pooled it
12.7field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
151 citing papers in PubMed, 1 synthesis or guideline pooled it, 254 citations in OpenAlex.
- Understanding heterogeneity in the pathogenesis and drug responses of ulcerative colitis through single-cell and spatial transcriptomics.Frontiers in immunology · 2026Pooled it
- Single-cell landscape of piglet lung response withVirulence · 2026Article
- Concerted changes in the pediatric single-cell intestinal ecosystem before and after anti-TNF blockade.eLife · 2026Article
- Dose-response framework for DSS-induced colitis in mice.iScience · 2026Article
- Leveraging Single-Cell and Spatial Transcriptomics in Gut Nutrition and Mucosal Immunology.The Journal of nutrition · 2026Article
- GZMK-expressing tissue-resident memory CD8+ T cells participate in human intestinal acute graft-versus-host disease.JCI insight · 2026Article
- Immune Repertoire Profiling Reveals Distinct Adaptive Immune Signatures of Dampness ZHENG Across Psoriasis, Rheumatoid Arthritis and Ulcerative Colitis.Cell proliferation · 2026Article
- IL-26-driven epigenetic remodeling promotes immune evasion in colorectal cancer.Nature communications · 2026Article
- Single-cell RNA sequencing of terminal ileal biopsies identifies signatures of Crohn's disease pathogenesis.Nature genetics · 2026Article
- Article
- Chenodeoxycholic acid redirects the bile acid synthetic pathway to limit pro-inflammatory neutrophil infiltration and alleviate colitis.Molecular therapy : the journal of the American Society of Gene Therapy · 2026Article
- Observational
- The roles and heterogeneity of CD8International journal of molecular medicine · 2026Review
- Spatial transcriptomics atlas of inflammatory bowel disease to guide implementation in research consortiums and clinical trials.Nature communications · 2026Article
- Article
- Regional and Sex-Dependent Immune Profiling Across the Colon in A Mouse Model of Ulcerative Colitis.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026Article
- Single-cell and spatial profiling reveal cDC2A-CXCL13Nature communications · 2026Article
- When Checkpoint Inhibitors Break Barriers: Mechanisms and Challenges of irAEs of the Skin, Gastrointestinal Tract, and Lung.Clinical cancer research : an official journal of the American Association for Cancer Research · 2026Review
- Fecal Detection of Calprotectin Subunits Links Inflammatory Bowel Disease Activity With Chronicity of Intestinal Inflammation.Gastroenterology · 2026Article
- Host genotypes interact with microbial communities to modulate gene expression in the human intestine.medRxiv : the preprint server for health sciences · 2026Article
91 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
Authors and funding
20 authors at 5 institutions in 3 countries.
Daniele Corridoni *Medical Research Council (MRC) Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine (WIMM), John Radcliffe Hospital, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0003-0251-2248
Agne Antanaviciute *Medical Research Council (MRC) Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine (WIMM), John Radcliffe Hospital, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0002-9019-2215
Tarun Gupta *Medical Research Council (MRC) Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine (WIMM), John Radcliffe Hospital, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0002-9235-8717
David Fawkner-CorbettMedical Research Council (MRC) Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine (WIMM), John Radcliffe Hospital, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0002-5273-3682
Anna AulicinoMedical Research Council (MRC) Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine (WIMM), John Radcliffe Hospital, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0002-3407-2796
Marta JagielowiczMedical Research Council (MRC) Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine (WIMM), John Radcliffe Hospital, University of Oxford, Oxford, UK.
Kaushal ParikhMedical Research Council (MRC) Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine (WIMM), John Radcliffe Hospital, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0002-3247-3676
Emmanouela RepapiComputational Biology Research Group, University of Oxford, John Radcliffe Hospital, Oxford, UK.ORCID http://orcid.org/0000-0001-8085-0731
Steve TaylorComputational Biology Research Group, University of Oxford, John Radcliffe Hospital, Oxford, UK.
Dai IshikawaDepartment of Gastroenterology, Juntendo University School of Medicine, Tokyo, Japan.ORCID http://orcid.org/0000-0002-1130-2210
Ryo HatanoDepartment of Therapy Development and Innovation for Immune Disorders and Cancers, Juntendo University, Tokyo, Japan.
Taketo YamadaDepartment of Pathology, Saitama Medical University, Saitama, Japan.
Wei XinDepartment of Pathology, Case Western Reserve University, Cleveland, OH, USA.ORCID http://orcid.org/0000-0003-0987-0443
Hubert SlawinskiWellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.
Rory BowdenWellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0001-8596-0366
Giorgio NapolitaniMedical Research Council (MRC) Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine (WIMM), John Radcliffe Hospital, University of Oxford, Oxford, UK.
Oliver BrainTranslational Gastroenterology Unit, John Radcliffe Hospital, University of Oxford, Oxford, UK.
Chikao MorimotoDepartment of Therapy Development and Innovation for Immune Disorders and Cancers, Juntendo University, Tokyo, Japan.
Hashem KoohyMedical Research Council (MRC) Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine (WIMM), John Radcliffe Hospital, University of Oxford, Oxford, UK. hashem.koohy@rdm.ox.ac.uk.ORCID http://orcid.org/0000-0002-3640-7043
Alison SimmonsMedical Research Council (MRC) Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine (WIMM), John Radcliffe Hospital, University of Oxford, Oxford, UK. alison.simmons@imm.ox.ac.uk.ORCID http://orcid.org/0000-0003-3454-0710
John Radcliffe Hospital · GBJuntendo University · JPCentre for Human Genetics · GBCase Western Reserve University · USSaitama Medical University · JP
Funding
Department of HealthMedical Research Council MC_PC_MR/S025952/1Medical Research Council MC_UU_00008/7Medical Research Council MC_UU_12010/7Medical Research Council MR/M00919X/1Medical Research Council MR/S036377/1Wellcome Trust 219523/Z/19/Z
Abstract
Colonic antigen-experienced lymphocytes such as tissue-resident memory CD8
Indexed as
AnimalsCD8-Positive T-LymphocytesColitis, UlcerativeColonFemaleGene Expression ProfilingHumansInterleukinsIntestinal MucosaMaleMiceMice, Inbred C57BLMice, TransgenicTranscriptomeTumor Necrosis Factor-alphaIL26 protein, humanInterleukinsTumor Necrosis Factor-alpha
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.