Evidence map›Paper›PMID 32747825›Full record

ArticleNature genetics2020

Landscape of G-quadruplex DNA structural regions in breast cancer.

Robert Hänsel-Hertsch, Angela Simeone, Abigail Shea, Winnie W I Hui, Katherine G Zyner, Giovanni Marsico, Oscar M Rueda, Alejandra Bruna, Alistair Martin, Xiaoyun Zhang and 4 more

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Nature genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 109 papers.

0numbers the graph read from it
0cells of the map it votes in
109citing papers in PubMed
10.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

109 citing papers in PubMed, 222 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. G-Quadruplexes: Structural Diversity and Emerging Roles in Biomolecular Condensation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  5. Review
  6. Unraveling G-Quadruplex and i-Motif Coexistence Within a Double-Stranded DNA.Angewandte Chemie (International ed. in English) · 2026
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
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  14. Article
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  16. Article
  17. Review
  18. Article
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  20. Article

49 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 3 countries.

Robert Hänsel-HertschCenter for Molecular Medicine Cologne, University of Cologne, Cologne, Germany.
Angela SimeoneCancer Research UK Cambridge Institute, Li Ka Shing Centre, University of Cambridge, Cambridge, UK.
Abigail SheaCancer Research UK Cambridge Institute, Li Ka Shing Centre, University of Cambridge, Cambridge, UK.
Winnie W I HuiCancer Research UK Cambridge Institute, Li Ka Shing Centre, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0001-8041-0218
Katherine G ZynerCancer Research UK Cambridge Institute, Li Ka Shing Centre, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0002-4997-0150
Giovanni MarsicoCancer Research UK Cambridge Institute, Li Ka Shing Centre, University of Cambridge, Cambridge, UK.
Oscar M RuedaCancer Research UK Cambridge Institute, Li Ka Shing Centre, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0003-0008-4884
Alejandra BrunaCancer Research UK Cambridge Institute, Li Ka Shing Centre, University of Cambridge, Cambridge, UK.
Alistair MartinCancer Research UK Cambridge Institute, Li Ka Shing Centre, University of Cambridge, Cambridge, UK.
Xiaoyun ZhangDepartment of Chemistry, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0002-4132-3573
Santosh AdhikariDepartment of Chemistry, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0002-1501-2106
David TannahillCancer Research UK Cambridge Institute, Li Ka Shing Centre, University of Cambridge, Cambridge, UK.
Carlos CaldasCancer Research UK Cambridge Institute, Li Ka Shing Centre, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0003-3547-1489
Shankar BalasubramanianCancer Research UK Cambridge Institute, Li Ka Shing Centre, University of Cambridge, Cambridge, UK. sb10031@cam.ac.uk.ORCID http://orcid.org/0000-0002-0281-5815
University of Cambridge · GBBabraham Institute · GBInstitute of Cancer Research · GBUniversity of Cologne · DE

Funding

Cancer Research UK 18618Cancer Research UK 19836Cancer Research UK 29567Cancer Research UK C14303/A17197Cancer Research UK C9681/A18618Cancer Research UK C9681/A29214Medical Research Council MC_UU_00002/16Wellcome Trust 209441/Z/17/Z
6 · The paper itself

Abstract

Response and resistance to anticancer therapies vary due to intertumor and intratumor heterogeneity

Indexed as

Breast NeoplasmsDNAFemaleGene Expression RegulationG-QuadruplexesHumansPromoter Regions, GeneticTranscription FactorsDNATranscription Factors

Identifiers

PMID32747825
OpenAlexW3047068833

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.