Evidence map›Paper›PMID 32747824›Full record

ArticleNature genetics2020

Analysis of Ugandan cervical carcinomas identifies human papillomavirus clade-specific epigenome and transcriptome landscapes.

Alessia Gagliardi, Vanessa L Porter, Zusheng Zong, Reanne Bowlby, Emma Titmuss, Constance Namirembe, Nicholas B Griner, Hilary Petrello, Jay Bowen, Simon K Chan and 22 more

Open access · greenAbstract read
In one paragraph

Article in Nature genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 76 citations in OpenAlex.

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  14. Viral oncogenesis in cancer: from mechanisms to therapeutics.Signal transduction and targeted therapy · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

32 authors at 13 institutions in 3 countries.

Alessia Gagliardi *Canada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, British Columbia, Canada.ORCID http://orcid.org/0000-0002-6024-503X
Vanessa L Porter *Canada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, British Columbia, Canada.ORCID http://orcid.org/0000-0002-7167-4884
Zusheng Zong *Canada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, British Columbia, Canada.
Reanne Bowlby *Canada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, British Columbia, Canada.
Emma Titmuss *Canada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, British Columbia, Canada.ORCID http://orcid.org/0000-0002-1993-6912
Constance NamirembeUganda Cancer Institute, Kampala, Uganda.ORCID http://orcid.org/0000-0001-5979-8465
Nicholas B GrinerOffice of Cancer Genomics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Hilary PetrelloNationwide Children's Hospital, Columbus, OH, USA.
Jay BowenNationwide Children's Hospital, Columbus, OH, USA.ORCID http://orcid.org/0000-0001-6861-9043
Simon K ChanCanada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, British Columbia, Canada.
Luka CulibrkCanada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, British Columbia, Canada.
Teresa M DarraghDepartment of Pathology, University of California at San Francisco, San Francisco, CA, USA.
Mark H StolerDepartment of Pathology, University of Virginia, Charlottesville, VA, USA.
Thomas C WrightDepartment of Pathology and Cell Biology, Columbia University, New York, NY, USA.
Patee GesuwanOffice of Cancer Genomics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Maureen A DyerFrederick National Laboratory for Cancer Research, Frederick, MD, USA.ORCID http://orcid.org/0000-0002-0681-3665
Yussanne MaCanada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, British Columbia, Canada.
Karen L MungallCanada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, British Columbia, Canada.
Steven J M JonesCanada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, British Columbia, Canada.ORCID http://orcid.org/0000-0003-3394-2208
Carolyn NakisigeUganda Cancer Institute, Kampala, Uganda.
Karen NovikCanada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, British Columbia, Canada.
Jackson OremUganda Cancer Institute, Kampala, Uganda.ORCID http://orcid.org/0000-0002-5366-9010
Martin OrigaUganda Cancer Institute, Kampala, Uganda.
Julie M Gastier-FosterNationwide Children's Hospital, Columbus, OH, USA.
Robert YarchoanOffice of HIV and AIDS Malignancy, National Cancer Institute, National Institues of Health, Bethesda, MD, USA.ORCID http://orcid.org/0000-0002-3057-1395
Corey CasperInfectious Disease Research Institute, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-3609-661X
Gordon B MillsKnight Cancer Institute, Oregon Health and Science University, Portland, OR, USA.ORCID http://orcid.org/0000-0002-0144-9614
Janet S RaderDepartment of Obstetrics and Gynecology, Medical College of Wisconsin, Milwaukee, WI, USA.
Akinyemi I OjesinaDepartment of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, USA.
Daniela S GerhardOffice of Cancer Genomics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Andrew J MungallCanada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, British Columbia, Canada.ORCID http://orcid.org/0000-0002-0905-2742
Marco A MarraCanada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, British Columbia, Canada. mmarra@bcgsc.ca.ORCID http://orcid.org/0000-0001-7146-7175
Canada's Michael Smith Genome Sciences Centre · CANational Institutes of Health · USUganda Cancer Institute · UGNationwide Children's Hospital · USUniversity of British Columbia · CAColumbia University · USFrederick National Laboratory for Cancer Research · USInfectious Disease Research Institute · USMedical College of Wisconsin · USOregon Health & Science University · USUniversity of Alabama at Birmingham · USUniversity of California, San Francisco · USUniversity of Virginia · US

Funding

University of Washington/Fred Hutch Center for AIDS ResearchP30AI027757 · NIAID · UNIVERSITY OF WASHINGTON · PI Kenneth Sherr · 1988 to 2026
$104.9M
AIDS and Cancer Specimen Resource (ACSR)UM1CA181255 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Jeffrey Michael Bethony, Anna Coghill · 2013 to 2026
$56.7M
Targeting the PI3K Signaling Pathway in Endometrial CarcinomaP50CA098258 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI BODURKA, DIANE · 2003 to 2020
$32.0M
The East Coast AIDS and Cancer Specimen ResourceU01CA066535 · NCI · GEORGE WASHINGTON UNIVERSITY · PI SILVER, SYLVIA · 1994 to 2012
$13.4M
AIDS and Cancer Specimen Resource Central Office and Data Coordinating CenterU01CA096230 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MCGRATH, MICHAEL SHANNON · 2002 to 2012
$7.1M
Integrative bioinformatics and functional characterization of oncogenic driver aberrations in cancerU01CA217842 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI DENEEN, BENJAMIN, MILLS, GORDON B. · 2017 to 2021
$3.6M
CCR NIH HHS HHSN261200800001CCIHR FDN-143288CIHR GSD-152374CIHR GSD-164207NCI NIH HHS HHSN261200800001ENCI NIH HHS HHSN261201500003CNCI NIH HHS HHSN261201500003INCI NIH HHS P50 CA098258NCI NIH HHS U01 CA066535NCI NIH HHS U01 CA096230NCI NIH HHS U01 CA217842NCI NIH HHS UM1 CA181255NIAID NIH HHS P30 AI027757
6 · The paper itself

Abstract

Cervical cancer is the most common cancer affecting sub-Saharan African women and is prevalent among HIV-positive (HIV

Indexed as

AdultAgedDNA MethylationEpigenomeFemaleHumansMiddle AgedPapillomaviridaePapillomavirus InfectionsPromoter Regions, GeneticSignal TransductionTranscriptomeUgandaUp-RegulationUterine Cervical Neoplasms

Identifiers

PMID32747824
PMCPMC7498180
OpenAlexW3046437178

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.