Evidence map›Paper›PMID 32747769›Full record

ArticleNature methods2020

High-sensitivity and high-specificity biomechanical imaging by stimulated Brillouin scattering microscopy.

Itay Remer, Roni Shaashoua, Netta Shemesh, Anat Ben-Zvi, Alberto Bilenca

Erratum issuedOpen access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Nature methods, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
6.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 110 citations in OpenAlex.

  1. Article
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  7. Harnessing quantum light for microscopic biomechanical imaging of cells and tissues.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  8. Stimulated Brillouin scattering flow cytometry.Biomedical optics express · 2024
    Article
  9. Article
  10. Diagnostic potential of blood plasma longitudinal viscosity measured using Brillouin light scattering.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  11. Review
  12. Article
  13. Article
  14. Corneal biomechanics and diagnostics: a review.International ophthalmology · 2024
    Review
  15. Article
  16. Brillouin microscopy.Nature reviews. Methods primers · 2024
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Itay RemerBiomedical Engineering Department, Ben-Gurion University of the Negev, Be'er-Sheva, Israel. remeri@post.bgu.ac.il.ORCID http://orcid.org/0000-0003-4669-782X
Roni ShaashouaBiomedical Engineering Department, Ben-Gurion University of the Negev, Be'er-Sheva, Israel.
Netta ShemeshDepartment of Life Sciences, Ben-Gurion University of the Negev, Be'er Sheva, Israel.
Anat Ben-ZviDepartment of Life Sciences, Ben-Gurion University of the Negev, Be'er Sheva, Israel.ORCID http://orcid.org/0000-0003-2477-6519
Alberto BilencaBiomedical Engineering Department, Ben-Gurion University of the Negev, Be'er-Sheva, Israel. bilenca@bgu.ac.il.ORCID http://orcid.org/0000-0003-3320-4731
Ben-Gurion University of the Negev · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Label-free, non-contact imaging with mechanical contrast and optical sectioning is a substantial challenge in microscopy. Spontaneous Brillouin scattering microscopy meets this challenge, but encounters a trade-off between acquisition speed and the specificity for biomechanical constituents with overlapping Brillouin bands. Stimulated Brillouin scattering microscopy overcomes this trade-off and enables the cross-sectional imaging of live Caenorhabditis elegans at the organ and subcellular levels, with both elasticity and viscosity contrasts at high specificity and with practical recording times.

Indexed as

Scattering, RadiationAnimalsBiomechanical PhenomenaCaenorhabditis elegansElasticityEscherichia coliMicroscopy, ConfocalViscosity

Identifiers

PMID32747769
OpenAlexW2979602725

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.