ArticleNature plants2020
Local auxin biosynthesis is required for root regeneration after wounding.
Article in Nature plants, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 47 papers.
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Who cites it
47 citing papers in PubMed, 107 citations in OpenAlex.
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- Towards an integrated molecular understanding of plant hormones.Journal of integrative plant biology · 2026Review
- Endophytic Flavobacterium promotes root hair development and enhances drought tolerance via an ERF-CEP5 hormonal regulatory module.Nature plants · 2026Article
- The Arabidopsis ARF3-AIP1/2-SAP18 module specifies the root stem cell niche in response to auxin.The Plant cell · 2026Article
- Dedifferentiation of Plant Cells: A Term Covering Multiple Pathways?Plants (Basel, Switzerland) · 2026Article
- Dynamic auxin maxima regulate male-to-hermaphrodite conversion and de novo meristem formation in the fern Ceratopteris gametophytes.PLoS biology · 2026Article
- Wounding induces multilayered barrier formation in mature leaves via phytohormone signalling and ATML1-mediated epidermal specification.Nature plants · 2025Article
- Plant genetic transformation: achievements, current status and future prospects.Plant biotechnology journal · 2025Review
- Damage activates EXG1 and RLP44 to suppress vascular differentiation during regeneration in Arabidopsis.Plant communications · 2025Article
- MDF Regulates a Network of Auxin-Dependent and Auxin-Independent Pathways of Adventitious Root Regeneration inPlant direct · 2025Article
- Nodule organogenesis in Medicago truncatula requires local stage-specific auxin biosynthesis and transport.Plant physiology · 2025Article
- MicroRNA control of stem cell reconstitution and growth in root regeneration.Nature plants · 2025Article
- Molecular regulation and domestication of parthenocarpy in cucumber.Nature plants · 2025Article
- The Combined Toxic Effects of Polystyrene Microplastics and Arsenate on Lettuce Under Hydroponic Conditions.Toxics · 2025Article
- De novo root regeneration from leaf explant: a mechanistic review of key factors behind cell fate transition.Planta · 2025Review
- Unlocking plant regeneration capacity: small signaling peptides are on aboard.Frontiers in plant science · 2025Article
- Supplementary far-red light enhances the quality and root development of double-root-cutting grafted watermelon seedlings.Frontiers in plant science · 2025Article
- Establishment and application of highly efficient regeneration, genetic transformation and genome editing system for cucurbitacins biosynthesis in Hemsleya chinensis.BMC plant biology · 2024Article
- Multi-scale mechanisms driving root regeneration: From regeneration competence to tissue repatterning.The Plant journal : for cell and molecular biology · 2024Review
- Plant regeneration in the new era: from molecular mechanisms to biotechnology applications.Science China. Life sciences · 2024Review
Corrections and comments
- Erratum issued
Authors and funding
8 authors at 4 institutions in 3 countries.
Funding
Abstract
The root meristem can regenerate following removal of its stem-cell niche by recruitment of remnant cells from the stump. Regeneration is initiated by rapid accumulation of auxin near the injury site but the source of this auxin is unknown. Here, we show that auxin accumulation arises from the activity of multiple auxin biosynthetic sources that are newly specified near the cut site and that their continuous activity is required for the regeneration process. Auxin synthesis is highly localized while PIN-mediated transport is dispensable for auxin accumulation and tip regeneration. Roots lacking the activity of the regeneration competence factor ERF115, or that are dissected at a zone of low regeneration potential, fail to activate local auxin sources. Remarkably, restoring auxin supply is sufficient to confer regeneration capacity to these recalcitrant tissues. We suggest that regeneration competence relies on the ability to specify new local auxin sources in a precise temporal pattern.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.