ArticleProceedings of the National Academy of Sciences of the United States of America2020
A temporal record of the past with a spectrum of time constants in the monkey entorhinal cortex.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.
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Who cites it
62 citing papers in PubMed, 107 citations in OpenAlex.
- Context-dependent abstraction of temporal relationships during naturalistic episodic memory.iScience · 2026Article
- Intrinsic timing, not temporal prediction, underlies ramping dynamics in visual and parietal cortex during passive behavior.Science advances · 2026Article
- Neural dynamics underlying minute-timescale persistent behaviour in the human brain.Nature human behaviour · 2026Article
- Remembering the "when": Hebbian memory models for the time of past events.PLoS computational biology · 2026Article
- Article
- Neural population dynamics and temporal context cells in macaque medial parietal cortex support temporal order memory.PLoS biology · 2026Article
- Boundary Vector Cells Encode a Future-Biased Spectrum of Positions in the Rat.bioRxiv : the preprint server for biology · 2026Article
- Article
- Intrinsic persistent firing in CA1 encodes elapsed time across behaviorally relevant scales.bioRxiv : the preprint server for biology · 2025Article
- Neural Representation of Episodic Time.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Review
- Covariant spatio-temporal receptive fields for spiking neural networks.Nature communications · 2025Article
- Dynamical mean-field theory for a highly heterogeneous neural population with graded persistent activity of the entorhinal cortex.PLoS computational biology · 2025Article
- Continuous Attractor Networks for Laplace Neural Manifolds.Computational brain & behavior · 2025Article
- A scalable reinforcement learning framework inspired by hippocampal memory mechanisms for efficient contextual and sequential decision making.Scientific reports · 2025Article
- Control Principles of Neural Dynamics Revealed by the Neurobiology of Timing.Annual review of neuroscience · 2025Review
- Sustained Hippocampal Theta Oscillations Reflect Experience-Dependent Learning in Backward Temporal Order Memory Retrieval.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Learning Temporal Relationships Between Symbols with Laplace Neural Manifolds.Computational brain & behavior · 2025Article
- Article
- Self-supervised learning of scale-invariant neural representations of space and time.Journal of computational neuroscience · 2025Article
- The influence of emotion on temporal context models.Cognition & emotion · 2025Review
2 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
Episodic memory is believed to be intimately related to our experience of the passage of time. Indeed, neurons in the hippocampus and other brain regions critical to episodic memory code for the passage of time at a range of timescales. The origin of this temporal signal, however, remains unclear. Here, we examined temporal responses in the entorhinal cortex of macaque monkeys as they viewed complex images. Many neurons in the entorhinal cortex were responsive to image onset, showing large deviations from baseline firing shortly after image onset but relaxing back to baseline at different rates. This range of relaxation rates allowed for the time since image onset to be decoded on the scale of seconds. Further, these neurons carried information about image content, suggesting that neurons in the entorhinal cortex carry information about not only when an event took place but also, the identity of that event. Taken together, these findings suggest that the primate entorhinal cortex uses a spectrum of time constants to construct a temporal record of the past in support of episodic memory.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.