Evidence map›Paper›PMID 32747427›Full record

ArticleJournal of bacteriology2020

The Endoribonuclease RNase E Coordinates Expression of mRNAs and Small Regulatory RNAs and Is Critical for the Virulence of Brucella abortus.

Lauren M Sheehan, James A Budnick, Jaquille Fyffe-Blair, Kellie A King, Robert E Settlage, Clayton C Caswell

Open access · greenAbstract read
In one paragraph

Article in Journal of bacteriology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. mBio · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. A comprehensive review of small regulatory RNAs inFrontiers in veterinary science · 2022
    Review
  10. Article
  11. Article
  12. Article
  13. Uncovering the Hidden Credentials ofMicrobiology and molecular biology reviews : MMBR · 2021
    Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Lauren M SheehanCenter for One Health Research, Virginia-Maryland College of Veterinary Medicine, Blacksburg, Virginia, USA.
James A BudnickCenter for One Health Research, Virginia-Maryland College of Veterinary Medicine, Blacksburg, Virginia, USA.
Jaquille Fyffe-BlairCenter for One Health Research, Virginia-Maryland College of Veterinary Medicine, Blacksburg, Virginia, USA.
Kellie A KingCenter for One Health Research, Virginia-Maryland College of Veterinary Medicine, Blacksburg, Virginia, USA.
Robert E SettlageAdvanced Research Computing, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, USA.ORCID 0000-0002-1354-7609
Clayton C CaswellCenter for One Health Research, Virginia-Maryland College of Veterinary Medicine, Blacksburg, Virginia, USA caswellc@vt.edu.ORCID 0000-0003-3793-8804
Virginia–Maryland College of Veterinary Medicine · USVirginia Tech · US

Funding

Characterization of a novel genetic pathway required for Brucella virulenceR15AI117648 · NIAID · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI CASWELL, CLAYTON C · 2015 to 2015
$459k
NIAID NIH HHS R15 AI117648
6 · The paper itself

Abstract

RNases are key regulatory components in prokaryotes, responsible for the degradation and maturation of specific RNA molecules at precise times. Specifically, RNases allow cells to cope with changes in their environment through rapid alteration of gene expression. To date, few RNases have been characterized in the mammalian pathogen

Indexed as

AnimalsBacterial ProteinsBrucella abortusBrucellosisEndoribonucleasesFemaleGene DeletionGene Expression Regulation, BacterialHumansMacrophagesMiceMice, Inbred BALB CRNA, MessengerRNA-SeqVirulenceBacterial ProteinsEndoribonucleasesribonuclease ERNA, MessengerBrucella abortusribonucleasessmall RNAs

Identifiers

PMID32747427
PMCPMC7515240
OpenAlexW3046380154

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.