Evidence map›Paper›PMID 32747214›Full record

ArticleVaccine2020

The Brighton Collaboration standardized template for collection of key information for benefit-risk assessment of inactivated viral vaccines.

Sonali Kochhar, Jean-Louis Excler, Denny Kim, James S Robertson, Patricia E Fast, Richard C Condit, Stephen Drew, David Wood, Marc Gurwith, Bettina Klug and 6 more

Open access · hybridAbstract read
In one paragraph

Article in Vaccine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Expecting the unexpected with COVID-19 vaccines.The Lancet. Infectious diseases · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 9 institutions in 5 countries.

Sonali KochharGlobal Healthcare Consulting, New Delhi, India; University of Washington, Seattle, WA, USA.
Jean-Louis ExclerInternational Vaccine Institute, Seoul, Republic of Korea.
Denny KimJanssen Pharmaceuticals, Titusville, NJ, USA.
James S RobertsonIndependent Adviser, UK.
Patricia E FastInternational AIDS Vaccine Initiative, New York, NY, USA; Stanford School of Medicine, Palo Alto, CA, USA.
Richard C ConditDepartment of Molecular Genetics and Microbiology, University of Florida, Gainesville, FL, USA.
Stephen DrewIndependent Adviser, USA.
David WoodIndependent Adviser, UK.
Marc GurwithBrighton Collaboration, A Program of the Task Force for Global Health, Decatur, GA, USA.
Bettina KlugPaul-Ehrlich-Institut, Federal Institute for Vaccines and Biomedicines, Langen, Germany.
Mike WhelanProject Leader, CEPI, UK.
Najwa Khuri-BulosUniversity of Jordan, Amman, Jordan.
Tamala Mallett MooreSanofi Pasteur, Swiftwater, PA, USA.
Emily R SmithBrighton Collaboration, A Program of the Task Force for Global Health, Decatur, GA, USA.
Robert T ChenBrighton Collaboration, A Program of the Task Force for Global Health, Decatur, GA, USA.
Brighton Collaboration Viral Vector Vaccines Safety Working Group (V3SWG). Electronic address: brightoncollaborationv3swg@gmail.com
The Task Force for Global Health · USInternational AIDS Vaccine Initiative · USInternational Vaccine Institute · KRJanssen (United States) · USPaul Ehrlich Institut · DESanofi (United States) · USUniversity of Florida · USUniversity of Jordan · JOUniversity of Washington · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inactivated viral vaccines have long been used in humans for diseases of global health threat and are now among the vaccines for COVID-19 under development. The Brighton Collaboration Viral Vector Vaccines Safety Working Group (V3SWG) has prepared a standardized template to describe the key considerations for the benefit-risk assessment of inactivated viral vaccines. This will help key stakeholders to assess potential safety issues and understand the benefit-risk of the vaccine platform. The standardized and structured assessment provided by the template would also help to contribute to improved communication and support public acceptance of licensed inactivated viral vaccines.

Indexed as

Risk AssessmentBetacoronavirusCivil DefenseCoronavirus InfectionsCOVID-19COVID-19 VaccinesDrug ApprovalGovernment RegulationHumansImmunogenicity, VaccineInternational CooperationPandemicsPatient SafetyPneumonia, ViralSARS-CoV-2Vaccines, InactivatedCOVID-19 VaccinesVaccines, InactivatedViral VaccinesBenefit-riskBrighton CollaborationCEPICOVID-19InactivatedSafetyTemplateVaccineVirus

Identifiers

PMID32747214
PMCPMC7834840
OpenAlexW3041371519

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.