Evidence map›Paper›PMID 32746887›Full record

ArticleBMC infectious diseases2020

Orbital abscess caused by Exophiala dermatitidis following posterior subtenon injection of triamcinolone acetonide: a case report and a review of literature related to Exophiala eye infections.

Chiharu Iwahashi, Hiroshi Eguchi, Fumika Hotta, Mayu Uezumi, Miki Sawa, Masatomo Kimura, Takashi Yaguchi, Shunji Kusaka

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Late-onsetMedical mycology case reports · 2026
    Article
  4. Article
  5. Article
  6. Fungal corneal abscess caused by Exophiala dermatitidis.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2023
    Article
  7. Eye fungal infections: a mini review.Archives of microbiology · 2023
    Review
  8. Orbital Abscess-Two Case Reports with Review.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2022
    Article
  9. Exophiala dermatitidis.World journal of clinical cases · 2021
    Article
  10. Mycotic Keratitis-A Global Threat from the Filamentous Fungi.Journal of fungi (Basel, Switzerland) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Chiharu IwahashiDepartment of Ophthalmology, Faculty of Medicine, Kindai University, 377-2, Ohonohigashi, Osakasayama-shi, Osaka, 589-8511, Japan.
Hiroshi EguchiDepartment of Ophthalmology, Faculty of Medicine, Kindai University, 377-2, Ohonohigashi, Osakasayama-shi, Osaka, 589-8511, Japan. hiroegu0113@gmail.com.ORCID https://orcid.org/0000-0002-4046-1413
Fumika HottaDepartment of Ophthalmology, Faculty of Medicine, Kindai University, 377-2, Ohonohigashi, Osakasayama-shi, Osaka, 589-8511, Japan.
Mayu UezumiDepartment of Ophthalmology, Sakai City Medical Center, 1-1-1, Ebaraji-cho, Nishi-ku, Sakai City, Osaka, 593-08304, Japan.
Miki SawaDepartment of Ophthalmology, Sakai City Medical Center, 1-1-1, Ebaraji-cho, Nishi-ku, Sakai City, Osaka, 593-08304, Japan.
Masatomo KimuraDepartment of Diagnostic Pathology, Kindai University Faculty of Medicine, 377-2, Ohnohigashi, Osakasayama, Osaka, 589-8511, Japan.
Takashi YaguchiMedical Mycology Research Center Chiba University, 1-8-1, Inohana, Chuo-ku, Chiba-shi, Chiba, 260-8673, Japan.
Shunji KusakaDepartment of Ophthalmology, Faculty of Medicine, Kindai University, 377-2, Ohonohigashi, Osakasayama-shi, Osaka, 589-8511, Japan.
Kindai University · JPSakai Municipal Hospital · JPChiba University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSubtenon injection of triamcinolone acetonide (STTA) has been widely adopted in the clinical setting of ophthalmology and its infectious complications are rare. However, orbital abscess following STTA has been reported in seven cases. Furthermore, although eye infections due to Exophiala species are uncommon, there have been 19 cases to date. E. jeanselmei, E. phaeomuriformis, E. werneckii, and E. dermatitidis have been reported to cause human eye infections; however, to the best of our knowledge, orbital abscess caused by E. dermatitidis has not yet been reported. We describe the first documented case of fungal orbital abscess caused by E. dermatitidis following STTA. We also review the related literature of orbital abscess following STTA, as well as eye infections caused by the four Exophiala species. CASE PRESENTATION: The patient was a 69-year-old Japanese woman with diabetic mellitus. She had a macular oedema in her right eye, which occurred secondary to branch retinal vein occlusion. An orbital abscess caused by E. dermatitidis occurred 4 months after the second STTA for the macular oedema, which was successfully treated by a surgical debridement and systemic administration of voriconazole.

conclusionsOur findings in the patient and from our literature survey caution ophthalmologists to the fact that STTA can cause fungal orbital infections, especially in diabetic patients. Furthermore, surgical treatment is one of the most important risk factors.

Indexed as

AbscessAgedAntifungal AgentsAnti-Inflammatory AgentsDermatitisExophialaEye InfectionsFemaleHumansMacular EdemaTriamcinolone AcetonideVoriconazoleAntifungal AgentsAnti-Inflammatory AgentsTriamcinolone AcetonideVoriconazoleExophiala dermatitidisOrbital abscessPseudallescheria boydii/Scedosporium apiospermum complexSubtenon injectionVoriconazole

Identifiers

PMID32746887
PMCPMC7398408
OpenAlexW3047020118

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.