Trial reportCritical care (London, England)2020
Chest physiotherapy improves lung aeration in hypersecretive critically ill patients: a pilot randomized physiological study.
Trial report in Critical care (London, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05751707 (The Role of HFCWO Via The Vest® Airway Clearance System in Addition to NIRT in the Treatment of Patient With Acute Respiratory Failure and Hypersecretion), which is not on this map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Role of HFCWO Via The Vest® Airway Clearance System in Addition to NIRT in the Treatment of Patient With Acute Respiratory Failure and Hypersecretion: Monocentric, Parallel Group, Controlled Randomized Clinical Trial
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- Effects of High-Frequency Chest Wall Oscillation on Acute Exacerbation of Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.International journal of chronic obstructive pulmonary disease · 2022Pooled it
- Thoracic electrical impedance tomography from technological promise to clinical reality: the Chinese experience.Journal of thoracic disease · 2026Review
- Effectiveness and Physiological Safety of a Lung Vibration Device for Airway Clearance in Patients with Sputum Retention: A Randomized Crossover Study.Life (Basel, Switzerland) · 2026Article
- High-frequency oscillation improves mucus clearance and airway resistance in mechanically ventilated patients: a randomized clinical trial.Annals of intensive care · 2026Article
- Interruption of enteral tube feeding during chest physiotherapy in critically ill adults: A scoping review.Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2026Review
- Chest physiotherapy protocol based on ultrasonic signs and its preliminary clinical application in patients with severe traumatic brain injury.Frontiers in neurology · 2026Article
- Recommendations for lung ventilation and perfusion assessment with chest electrical impedance tomography in critically ill adult patients: an international evidence-based and expert Delphi consensus study.EClinicalMedicine · 2025Article
- Lung electrical impedance tomography during positioning, weaning and chest physiotherapy in mechanically ventilated critically ill patients: a narrative review.Annals of intensive care · 2025Review
- Consensus Statements on Airway Clearance Interventions in Intubated Critically Ill Patients-Protocol for a Delphi Study.Life (Basel, Switzerland) · 2025Article
- Monitoring of Regional Ventilation Distribution Using Electrical Impedance Tomography in Pediatric Patients With Chest Physiotherapy-A Feasibility Study.Pediatric pulmonology · 2025Article
- Article
- Observation on the application effect of chest physical therapy based on lung ultrasound signs in the respiratory management of mechanically ventilated patients.Frontiers in medicine · 2025Article
- High-frequency percussive ventilation in acute respiratory failure.ERJ open research · 2024Article
- Evaluating the impact of electrode planes on regional lung function assessment.Frontiers in physiology · 2024Article
- Benefits of secretion clearance with high frequency percussive ventilation in tracheostomized critically ill patients: a pilot study.Journal of clinical monitoring and computing · 2023Article
- Appropriate time to radical surgery for colorectal cancer patients complicated with newly onset cerebral infarction: a propensity score matching analysis.Scientific reports · 2023Article
- Chest physiotherapy guided by electrical impedance tomography in high-dependency unit patients with pulmonary diseases: an introduction of methodology and feasibility.Critical care (London, England) · 2023Article
- Expert opinion document: "Electrical impedance tomography: applications from the intensive care unit and beyond".Journal of anesthesia, analgesia and critical care · 2022Review
- Editorial: CardioPulmonary Physiology: Novel Approaches to Pulmonary Function and Critical Care.Frontiers in physiology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBesides airway suctioning, patients undergoing invasive mechanical ventilation (iMV) benefit of different combinations of chest physiotherapy techniques, to improve mucus removal. To date, little is known about the clearance effects of oscillating devices on patients with acute respiratory failure undergoing iMV. This study aimed to assess (1) the effects of high-frequency chest wall oscillation (HFCWO) on lung aeration and ventilation distribution, as assessed by electrical impedance tomography (EIT), and (2) the effect of the association of HFCWO with recruitment manoeuvres (RM).
methodsSixty critically ill patients, 30 classified as normosecretive and 30 as hypersecretive, who received ≥ 48 h of iMV, underwent HFCWO; patients from both subgroups were randomized to receive RM or not, according to two separated randomization sequences. We therefore obtained four arms of 15 patients each. After baseline record (T0), HFCWO was applied for 10 min. At the end of the treatment (T1) or after 1 (T2) and 3 h (T3), EIT data were recorded. At the beginning of each step, closed tracheobronchial suctioning was performed. In the RM subgroup, tracheobronchial suctioning was followed by application of 30 cmH
resultsΔTIV and COG did not differ between normosecretive and hypersecretive patients. Compared to T0, ΔEELI significantly increased in hypersecretive patients at T2 and T3, irrespective of the RM; on the contrary, no differences were observed in normosecretive patients. No differences of ABGs were recorded.
conclusionsIn hypersecretive patients, HFCWO significantly improved aeration of the dorsal lung region, without affecting ABGs. The application of RM did not provide any further improvements.
trial registrationProspectively registered at the Australian New Zealand Clinical Trial Registry ( www.anzctr.org.au ; number of registration: ACTRN12615001257550; date of registration: 17th November 2015).
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.