ArticleIEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society2020
Motor Modules are Impacted by the Number of Reaching Directions Included in the Analysis.
Article in IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed, 8 citations in OpenAlex.
- Manipulating abnormal synergistic coupling of joint torques through force applications at the Hand: A Simulation-Based study.Journal of biomechanics · 2022Article
- Design of an Isometric End-Point Force Control Task for Electromyography Normalization and Muscle Synergy Extraction From the Upper Limb Without Maximum Voluntary Contraction.Frontiers in human neuroscience · 2022Article
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
Muscle synergy analysis is commonly used to study how the nervous system coordinates the activation of a large number of muscles during human reaching. In synergy analysis, muscle activation data collected from various reaching directions are subjected to dimensionality reduction techniques to extract muscle synergies. Typically, muscle activation data are obtained only from a limited set of reaches with an inherent assumption that the performed reaches adequately represent all possible reaches. In this study, we investigated how the number of reaching directions included in the synergy analysis influences the validity of the extracted synergies. We used a musculoskeletal model to compute muscle activations required to perform 36 evenly spaced planar reaches. Nonnegative matrix factorization (NMF) and principal component analysis (PCA) were then used to extract reference synergies. We then selected several subsets of reaches and compared the ability of the extracted synergies from each subset to represent the muscle activation from all 36 reaches. We found that 6 reaches were required to extract valid synergies, and a further reduction in the number of reaches changed the composition of the resulting synergies. Further, we found that the choice of reaching directions included in the analysis for a given number of reaches also affected the validity of the extracted synergies. These findings indicate that both the number and the choice of reaching directions included in the analysis impacted the validity of the extracted synergies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.