Evidence map›Paper›PMID 32746100›Full record

ArticleIEEE transactions on medical imaging2020

Improved Low-Count Quantitative PET Reconstruction With an Iterative Neural Network.

Hongki Lim, Il Yong Chun, Yuni K Dewaraja, Jeffrey A Fessler

Abstract read
In one paragraph

Article in IEEE transactions on medical imaging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. AI for PET image reconstruction.The British journal of radiology · 2023
    Review
  13. Training End-to-End Unrolled Iterative Neural Networks for SPECT Image Reconstruction.IEEE transactions on radiation and plasma medical sciences · 2023
    Article
  14. Momentum-Net: Fast and Convergent Iterative Neural Network for Inverse Problems.IEEE transactions on pattern analysis and machine intelligence · 2023
    Article
  15. Article
  16. Article
  17. Deep Kernel Representation for Image Reconstruction in PET.IEEE transactions on medical imaging · 2022
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hongki Lim
Il Yong Chun
Yuni K Dewaraja
Jeffrey A Fessler

Funding

Imaging and Dosimetry of Yttrium-90 for Personalized Cancer TreatmentR01EB022075 · NIBIB · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DEWARAJA, YUNI K · 2016 to 2023
$4.7M
NIBIB NIH HHS R01 EB022075
6 · The paper itself

Abstract

Image reconstruction in low-count PET is particularly challenging because gammas from natural radioactivity in Lu-based crystals cause high random fractions that lower the measurement signal-to-noise-ratio (SNR). In model-based image reconstruction (MBIR), using more iterations of an unregularized method may increase the noise, so incorporating regularization into the image reconstruction is desirable to control the noise. New regularization methods based on learned convolutional operators are emerging in MBIR. We modify the architecture of an iterative neural network, BCD-Net, for PET MBIR, and demonstrate the efficacy of the trained BCD-Net using XCAT phantom data that simulates the low true coincidence count-rates with high random fractions typical for Y-90 PET patient imaging after Y-90 microsphere radioembolization. Numerical results show that the proposed BCD-Net significantly improves CNR and RMSE of the reconstructed images compared to MBIR methods using non-trained regularizers, total variation (TV) and non-local means (NLM). Moreover, BCD-Net successfully generalizes to test data that differs from the training data. Improvements were also demonstrated for the clinically relevant phantom measurement data where we used training and testing datasets having very different activity distributions and count-levels.

Indexed as

Image Processing, Computer-AssistedYttrium RadioisotopesAlgorithmsHumansNeural Networks, ComputerPhantoms, ImagingPositron-Emission TomographyRadiation DosageSignal-To-Noise RatioYttrium-90Yttrium Radioisotopes

Identifiers

PMID32746100
PMCPMC7685233

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.