Evidence map›Paper›PMID 32745887›Full record

ArticleEpilepsy research2020

Delays and disparities in diagnosis for adults with epilepsy: Findings from U.S. Medicaid data.

Wyatt P Bensken, Suparna M Navale, Angeline S Andrew, Barbara C Jobst, Martha Sajatovic, Siran M Koroukian

Abstract read
In one paragraph

Article in Epilepsy research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Prognosis of adults and children following a first unprovoked seizure.The Cochrane database of systematic reviews · 2023
    Pooled it
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  16. Treatment gaps in epilepsy.Frontiers in epidemiology · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wyatt P BenskenDepartment of Population and Quantitative Health Sciences, School of Medicine, Case Western Reserve University, Cleveland, OH, United States. Electronic address: wpb27@case.edu.
Suparna M NavaleDepartment of Population and Quantitative Health Sciences, School of Medicine, Case Western Reserve University, Cleveland, OH, United States.
Angeline S AndrewDepartment of Neurology: Geisel School of Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, NH, United States.
Barbara C JobstDepartment of Neurology: Geisel School of Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, NH, United States.
Martha SajatovicDepartments of Neurology and Psychiatry: University Hospitals Cleveland Medical Center, School of Medicine, Case Western Reserve University, Cleveland, OH, United States.
Siran M KoroukianDepartment of Population and Quantitative Health Sciences, School of Medicine, Case Western Reserve University, Cleveland, OH, United States.

Funding

TUMOR METABOLISM PROGRAMP30CA043703 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI Amar Desai · 1987 to 2026
$142.3M
Prevention Research Center for Healthy NeighborhoodsU48DP005030 · DP · CASE WESTERN RESERVE UNIVERSITY · PI BORAWSKI, ELAINE A. · 2014 to 2018
$6.8M
Multi-Level Interventions to Reduce Caries Disparities in Primary Care SettingsUH3DE025487 · NIDCR · CASE WESTERN RESERVE UNIVERSITY · PI NELSON, SUCHITRA S. · 2017 to 2021
$5.6M
Identifying Electronic Phenotypes associated with Patient Health Outcomes of Interhospital Transfer PatientsR15NR017792 · NINR · CASE WESTERN RESERVE UNIVERSITY · PI REIMER, ANDREW PAUL · 2018 to 2018
$477k
NCCDPHP CDC HHS U48 DP005030NCI NIH HHS P30 CA043703NIDCR NIH HHS UH3 DE025487NINR NIH HHS R15 NR017792
6 · The paper itself

Abstract

objectiveTo identify disparities in care pathways and time from first seizure to epilepsy diagnosis, we examined 2010-2014 Medicaid claims (including pharmacy) data from 16 States for individuals with incident epilepsy.

methodsWe identified adults (18-64) with an incident epilepsy diagnosis from 1/2012 through 6/2014. These individuals were enrolled in Medicaid for the entire study period and had no history of anti-epileptic drug (AED) use before their first seizure claim. We identified care pathways and calculated the duration from initial seizure to epilepsy diagnosis. We tested associations between these pathways and race/ethnicity, as well as time differences between care pathways using a Chi-squared and Kruskal-Wallis tests.

resultsThe 14,337 adults followed five different care pathways. Their overall median duration from first seizure code to epilepsy diagnosis code was 19.0 months (interquartile range: 4.6, 30.4), and 56.0% filled an AED prescription. Some minorities were more likely to follow pathways with increased durations and delay to diagnosis, and the duration to diagnosis varied significantly across the care pathways. SIGNIFICANCE: The many different care pathways seen in people with epilepsy show substantial and significant time delays between first seizure diagnosis and epilepsy diagnosis, including significant racial/ethnic disparities that warrant attention.

Indexed as

AdolescentAdultDatabases, FactualData Interpretation, StatisticalEpilepsyFemaleHealthcare DisparitiesHumansMaleMedicaidMiddle AgedTime-to-TreatmentUnited StatesYoung AdultAnti-epileptic drugDiagnosisDiagnosis delayDisparitiesMedicaidTime to diagnosis

Identifiers

PMID32745887
PMCPMC7998893

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.