Evidence map›Paper›PMID 32745836›Full record

ArticleDrug and alcohol dependence2020

Trajectories of cannabis use and risk for opioid misuse in a young adult urban cohort.

Beth A Reboussin, Jill A Rabinowitz, Johannes Thrul, Brion Maher, Kerry M Green, Nicholas S Ialongo

Open access · greenAbstract read
In one paragraph

Article in Drug and alcohol dependence, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 17 citations in OpenAlex.

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  10. Adult Psychiatric, Substance, and Functional Outcomes of Different Definitions of Early Cannabis Use.Journal of the American Academy of Child and Adolescent Psychiatry · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Beth A ReboussinDepartment of Biostatistics and Data Science, Wake Forest School of Medicine, Winston-Salem, NC, USA. Electronic address: brebouss@wakehealth.edu.
Jill A RabinowitzDepartment of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore MD, USA.
Johannes ThrulDepartment of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore MD, USA.
Brion MaherDepartment of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore MD, USA.
Kerry M GreenDepartment of Behavioral and Community Health, University of Maryland School of Public Health, College Park, MD, USA.
Nicholas S IalongoDepartment of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore MD, USA.
Johns Hopkins University · USUniversity of Maryland, College Park · USWake Forest University · US

Funding

Development & Malleability from Childhood to AdulthoodR01DA044184 · NIDA · JOHNS HOPKINS UNIVERSITY · PI IALONGO, NICHOLAS S · 2018 to 2022
$3.9M
Progression and Clustering of Marijuana Use in African American NeighborhoodsR01DA032550 · NIDA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI REBOUSSIN, BETH A. · 2012 to 2018
$1.3M
NIDA NIH HHS R01 DA032550NIDA NIH HHS R01 DA044184
6 · The paper itself

Abstract

backgroundAlthough much of the attention surrounding the opioid epidemic has focused on rural and suburban Whites and prescription opioids, heroin overdoses among urban Blacks are on the rise. While some argue that legalization of cannabis will combat the epidemic, there are concerns it ignores the shift in the epidemic and could increase vulnerability to opioid misuse. The goal of this study is to examine the association between cannabis use from adolescence to young adulthood with opioid misuse in a primarily urban Black cohort.

methodsData are from a study of 580 youth (87 % Black and 71 % low SES) residing in Baltimore City followed from ages 6-26. Cannabis trajectories were identified between ages 14-26 using group-based trajectory modeling. Logistic regressions were conducted to examine the impact of trajectories on opioid misuse in young adulthood adjusting for individual, neighborhood and peer factors. Opioid misuse was defined as using heroin or narcotics or painkillers without a prescription between ages 19-26.

resultsFour cannabis trajectories were identified: Low/Non-Users (59.7 %), Adolescent Onset Limited (19.5 %), Young Adult Onset (10.8 %), and Adolescent Onset Chronic (10.0 %). Adolescent Onset Chronic cannabis users had the highest rate of opioid misuse (44.8 %) followed by Adolescent Onset Limited (18.8 %), Young Adult Onset (14.8 %) and Low/Non-Users (8.3 %). Prevalences were significantly higher for Adolescent Onset groups relative to Low/Non-Users even after adjustment for individual, neighborhood and peer factors.

conclusionsAdolescent onset cannabis use is associated with opioid misuse in young adulthood among urban Blacks even after adjustment for socioecological factors associated with opioid misuse.

Indexed as

AdolescentAdultAnalgesics, OpioidBlack or African AmericanCannabisChildCohort StudiesDrug OverdoseFemaleHeroinHumansMaleMarijuana SmokingMotivationOpioid-Related DisordersPeer GroupAnalgesics, OpioidHeroinBlacksCannabisLongitudinal patternsOpioidsUrban

Identifiers

PMID32745836
PMCPMC8420929
OpenAlexW3043951502

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.