Evidence map›Paper›PMID 32745811›Full record

ReviewInfection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases2021

Genetic comparison among various coronavirus strains for the identification of potential vaccine targets of SARS-CoV2.

Navpreet Kaur, Rimaljot Singh, Zahid Dar, Rakesh Kumar Bijarnia, Neelima Dhingra, Tanzeer Kaur

Open access · greenAbstract readReview
In one paragraph

Review in Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed
2.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 115 citations in OpenAlex.

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  16. SARS-CoV-2 and the DNA damage response.The Journal of general virology · 2023
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2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Navpreet KaurDepartment of Biophysics, Panjab University, Chandigarh, India.
Rimaljot SinghDepartment of Biophysics, Panjab University, Chandigarh, India.
Zahid DarUniversity Institute of Pharmaceutical Sciences, Panjab University, Chandigarh, India.
Rakesh Kumar BijarniaMedzome Life Sciencez Pvt.Ltd., Baddi, Himachal Pradesh, India.
Neelima DhingraUniversity Institute of Pharmaceutical Sciences, Panjab University, Chandigarh, India.
Tanzeer KaurDepartment of Biophysics, Panjab University, Chandigarh, India. Electronic address: tanzeer.kaur@gmail.com.
Panjab University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

On-going pandemic pneumonia outbreak COVID-19 has raised an urgent public health issue worldwide impacting millions of people with a continuous increase in both morbidity and mortality. The causative agent of this disease is identified and named as SARS-CoV2 because of its genetic relatedness to SARS-CoV species that was responsible for the 2003 coronavirus outbreak. The immense spread of the disease in a very small period demands urgent development of therapeutic and prophylactic interventions for the treatment of SARS-CoV2 infected patients. A plethora of research is being conducted globally on this novel coronavirus strain to gain knowledge about its origin, evolutionary history, and phylogeny. This review is an effort to compare genetic similarities and diversifications among coronavirus strains, which can hint towards the susceptible antigen targets of SARS-CoV2 to come up with the potential therapeutic and prophylactic interventions for the prevention of this public threat.

Indexed as

Genes, ViralAngiotensin-Converting Enzyme 2COVID-19 VaccinesSARS-CoV-2Species SpecificityViral ProteinsACE2 protein, humanAngiotensin-Converting Enzyme 2COVID-19 VaccinesViral ProteinsCOVID-19ER stressGenomic comparisonSARS-CoV2Target antigenic sitesVaccine development

Identifiers

PMID32745811
PMCPMC7395230
OpenAlexW3046558543

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.