Evidence map›Paper›PMID 32745304›Full record

ArticleEuropean journal of haematology2020

Outcome of COVID-19 in multiple myeloma patients in relation to treatment.

Katharina Helene Susek, Charlotte Gran, Hans-Gustaf Ljunggren, Evren Alici, Hareth Nahi

Open access · hybridAbstract read
In one paragraph

Article in European journal of haematology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
2.3field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Katharina Helene SusekCenter for Hematology and Regenerative Medicine, Department of Medicine, Karolinska Institute, Stockholm, Sweden.ORCID https://orcid.org/0000-0003-2430-0748
Charlotte GranCenter for Hematology and Regenerative Medicine, Department of Medicine, Karolinska Institute, Stockholm, Sweden.ORCID https://orcid.org/0000-0002-6069-6615
Hans-Gustaf LjunggrenCenter for Infectious Medicine, Department of Medicine, Karolinska Institute, Stockholm, Sweden.ORCID https://orcid.org/0000-0003-0908-7387
Evren AliciCenter for Hematology and Regenerative Medicine, Department of Medicine, Karolinska Institute, Stockholm, Sweden.ORCID https://orcid.org/0000-0001-5307-6648
Hareth NahiCenter for Hematology and Regenerative Medicine, Department of Medicine, Karolinska Institute, Stockholm, Sweden.ORCID https://orcid.org/0000-0003-4711-5094
Karolinska University Hospital · SEKarolinska Institutet · SE

Funding

Cancerfonden 190190 Pj01VINNOVA 2019-00056
6 · The paper itself

Abstract

COVID-19 has emerged as a global pandemic. Cancer patients have been reported to be at higher risk for adverse outcome of COVID-19. Studies are ongoing to decipher the risk factors and risk groups among cancer patients as well as strategies to refine treatment approaches. Here, we report eight patients with multiple myeloma that underwent immunomodulatory therapies with daratumumab or lenalidomide-based combination treatments and one patient with smoldering multiple myeloma, all of which presented with symptomatic COVID-19. We report that patients that succumbed to COVID-19 presented with either progressive tumor disease under daratumumab treatment or were in remission under lenalidomide-dexamethasone treatment.

Indexed as

Antibodies, MonoclonalAntineoplastic Combined Chemotherapy ProtocolsBetacoronavirusCohort StudiesCoronavirus InfectionsCOVID-19DexamethasoneDisease ProgressionFemaleHumansImmunomodulationLenalidomideMaleMiddle AgedMultiple MyelomaPandemicsAntibodies, MonoclonaldaratumumabDexamethasoneLenalidomideThalidomideimmunologyinfectious diseasesmultiple myelomaplasma cell neoplasms

Identifiers

PMID32745304
PMCPMC7436812
OpenAlexW3046891979

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.