Evidence map›Paper›PMID 32745138›Full record

ArticlePloS one2020

Negative effect of methyl bromide fumigation work on the central nervous system.

Min-Goo Park, Jungmi Choi, Young-Seoub Hong, Chung Gyoo Park, Byoung-Gwon Kim, Se-Young Lee, Hyoun-Ju Lim, Hyoung-Ho Mo, Eunjo Lim, Wonseok Cha

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
7.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Insecticidal and biochemical effects ofFrontiers in plant science · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Chemical Composition ofMolecules (Basel, Switzerland) · 2021
    Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Min-Goo ParkDepartment of Plant Quarantine, Division of Pest Control, Animal and Plant Quarantine Agency (APQA), Gimcheon-si, Gyeongsangbuk-do, Republic of Korea.ORCID 0000-0003-2479-3693
Jungmi ChoiHuman Anti-Aging Standards Research Institute, Uiryeong-gun, Gyeongsangnam-do, Republic of Korea.ORCID 0000-0002-5287-7942
Young-Seoub HongDepartment of Preventive Medicine, College of Medicine, Dong-A University, Busan, Republic of Korea.
Chung Gyoo ParkInstitute of Life Science (BK21+ Program), Gyeongsang National University, Jinju, Gyeongnam, Republic of Korea.
Byoung-Gwon KimDepartment of Preventive Medicine, College of Medicine, Dong-A University, Busan, Republic of Korea.
Se-Young LeeHeavy Metal Exposure Environmental Health Center, Dong-A University, Busan, Republic of Korea.
Hyoun-Ju LimHeavy Metal Exposure Environmental Health Center, Dong-A University, Busan, Republic of Korea.
Hyoung-Ho MoDepartment of Plant Quarantine, Division of Pest Control, Animal and Plant Quarantine Agency (APQA), Gimcheon-si, Gyeongsangbuk-do, Republic of Korea.
Eunjo LimHuman Anti-Aging Standards Research Institute, Uiryeong-gun, Gyeongsangnam-do, Republic of Korea.
Wonseok ChaHuman Anti-Aging Standards Research Institute, Uiryeong-gun, Gyeongsangnam-do, Republic of Korea.ORCID 0000-0002-3625-2723
Dong-A University · KRKorea Research Institute of Standards and Science · KRGyeongsang National University · KRAnimal and Plant Quarantine Agency · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Methyl bromide (MB) is a fumigant that has been widely used for killing pests on plants in trade, soils, and structures worldwide due to its excellent permeability and insecticidal effect; however, MB should be replaced because it is an ozone-depleting substance. It is well-known that MB is highly toxic and hazardous to workers, but the effects of exposure in asymptomatic workers have not been explored. The purpose of this study is to investigate the impact of MB fumigation on the health of fumigators at a sensitive level. The electroencephalogram (EEG) and urinary bromide ion levels of 44 fumigators (the study group) and 20 inspectors (the control) were measured before and after fumigation work from February to August 2019 in Busan, Korea. The mean post-work concentration of bromide ion (18.311 μg/mg CRE) in the fumigators was significantly increased from the pre-work level (7.390 μg/mg CRE) (P<0.001). The fumigator post-work median frequencies (MDF) and alpha-to-theta ratios (ATR) of EEG index were significantly decreased compared to the pre-work values (P<0.05 for all indices). In contrast, there were no significant differences in inspector EEG indices and urinary bromide ion. The urinary bromide ion levels in all the subjects were negatively correlated with MDF (P = 0.032). In conclusion, fumigators' EEG indices and urinary bromide ion suggested that occupational exposure to MB negatively affected the health of workers, although the workers were asymptomatic.

Indexed as

AdultBromidesElectrocardiographyFemaleFumigationHumansHydrocarbons, BrominatedInsecticidesMaleMiddle AgedOccupational ExposureBromidesHydrocarbons, BrominatedInsecticidesmethyl bromide

Identifiers

PMID32745138
PMCPMC7398500
OpenAlexW3047133221

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.