SynthesisPsychological bulletin2020
Biological aging in childhood and adolescence following experiences of threat and deprivation: A systematic review and meta-analysis.
Synthesis in Psychological bulletin, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 227 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
227 citing papers in PubMed, 7 syntheses or guidelines pooled it, 390 citations in OpenAlex.
- Dimensions of early life adversity and cardiometabolic health in adulthood: A systematic review and meta-analysis.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2026Pooled it
- The intergenerational effects of low parental socio-economic position on cardiometabolic and inflammatory outcomes: A systematic review and meta-analysis.European journal of clinical investigation · 2026Pooled it
- The Impact of Adverse Childhood Experiences on Cognitive Control Across the Lifespan: A Systematic Review and Meta-analysis of Prospective Studies.Trauma, violence & abuse · 2025Pooled it
- Parental Deprivation- and Threat-Based Factors Associated with Youth Emotion-Based Neurocircuitry and Externalizing Behavior: A Systematic Review.Research on child and adolescent psychopathology · 2024Pooled it
- Early biological and psychosocial factors associated with PTSD onset and persistence in youth.European journal of psychotraumatology · 2024Pooled it
- Association between Childhood Exposure to Family Violence and Telomere Length: A Meta-Analysis.International journal of environmental research and public health · 2022Pooled it
- Neurostructural traces of early life adversities: A meta-analysis exploring age- and adversity-specific effects.Neuroscience and biobehavioral reviews · 2022Pooled it
- Telomere trajectories from early adolescence to adulthood following early institutionalization: Protective effects of foster care in the Bucharest Early Intervention Project.Psychoneuroendocrinology · 2026Trial
- Parenting Practices May Buffer the Impact of Adversity on Epigenetic Age Acceleration Among Young Children With Developmental Delays.Psychological science · 2023Trial
- Physiological Age and Homeostatic Dysregulation Following Child Maltreatment in Youth.Molecular psychiatry · 2026Article
- Developmental Care in the Early Years in Pediatric Intensive Care Patients as a Strategy to Mitigate Pediatric Post-Intensive-Care Syndrome: A Narrative Review.Journal of intensive care medicine · 2026Review
- Dimensions of early life adversity and accelerated biological aging in adolescents: an examination of fear-related mechanisms.Journal of behavioral medicine · 2026Article
- Early Adversity Imprints Multisystem Biological Aging: A Longitudinal Study of Adversity Dimensions and Aging Phenotypes Across Adolescence.Biological psychiatry global open science · 2026Article
- The Transdiagnostic Association Between Childhood Trauma and Accelerated Brain Aging in Two Independent Datasets.Schizophrenia bulletin · 2026Article
- Dimensions of Early-Life Adversity and Attention Biases in Childhood and Adolescence: A Systematic Review.Clinical child and family psychology review · 2026Review
- Childhood adversity and psychotic-like experiences in adolescence: Investigating a pathway via disrupted pubertal and grey matter development.JCPP advances · 2026Article
- Primary tooth emergence in young children is associated with a stress biomarker.Journal of developmental origins of health and disease · 2026Article
- Early life adversity and cardiometabolic risk in adolescents: Comparison of dimensional and cumulative approaches to adversity.Social science & medicine (1982) · 2026Article
- Adversity and adolescent brain development: differential associations with grey and white matter across two longitudinal cohorts.bioRxiv : the preprint server for biology · 2026Article
- Childhood socioeconomic status and changes in biological aging across mid-to-later life.Social science & medicine (1982) · 2026Article
167 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
Life history theory argues that exposure to early life adversity (ELA) accelerates development, although existing evidence for this varies. We present a meta-analysis and systematic review testing the hypothesis that ELA involving threat (e.g., violence exposure) will be associated with accelerated biological aging across multiple metrics, whereas exposure to deprivation (e.g., neglect, institutional rearing) and low-socioeconomic status (SES) will not. We meta-analyze 54 studies (
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.