Evidence map›Paper›PMID 32744531›Full record

ArticleJournal of visualized experiments : JoVE2020

A MRI-Based Toolbox for Neurosurgical Planning in Nonhuman Primates.

William K S Ojemann, Devon J Griggs, Zachary Ip, Olivya Caballero, Hesamoddin Jahanian, Susana Martinez-Conde, Stephen Macknik, Azadeh Yazdan-Shahmorad

Abstract readVideo-Audio Media
In one paragraph

Article in Journal of visualized experiments : JoVE, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. A Neural Implant Design Toolbox for Nonhuman Primates.Journal of visualized experiments : JoVE · 2024
    Article
  5. Review
  6. Article
  7. Demonstration of an Optimized Large-scale Optogenetic Cortical Interface for Non-human Primates.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2022
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

William K S OjemannBioengineering Department, University of Washington; Washington National Primate Research Center, University of Washington.
Devon J GriggsWashington National Primate Research Center, University of Washington; Electrical and Computer Engineering Department, University of Washington.
Zachary IpBioengineering Department, University of Washington; Washington National Primate Research Center, University of Washington.
Olivya CaballeroDepartment of Ophthalmology, SUNY Downstate Health Sciences University.
Hesamoddin JahanianRadiology Department, University of Washington.
Susana Martinez-CondeDepartment of Ophthalmology, SUNY Downstate Health Sciences University.
Stephen MacknikDepartment of Ophthalmology, SUNY Downstate Health Sciences University.
Azadeh Yazdan-ShahmoradBioengineering Department, University of Washington; Washington National Primate Research Center, University of Washington; Electrical and Computer Engineering Department, University of Washington; azadehy@uw.edu.

Funding

Washington National Primate Research CenterP51OD010425 · OD · UNIVERSITY OF WASHINGTON · PI Mari Ostendorf · 2012 to 2026
$201.8M
Interdisciplinary Engineering Career Development Center in Movement and Rehabilitation SciencesK12HD073945 · NICHD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI DEWALD, JULIUS P, REINKENSMEYER, DAVID JAY · 2012 to 2021
$7.9M
NICHD NIH HHS K12 HD073945NIH HHS P51 OD010425
6 · The paper itself

Abstract

In this paper, we outline a method for surgical preparation that allows for the practical planning of a variety of neurosurgeries in NHPs solely using data extracted from magnetic resonance imaging (MRI). This protocol allows for the generation of 3D printed anatomically accurate physical models of the brain and skull, as well as an agarose gel model of the brain modeling some of the mechanical properties of the brain. These models can be extracted from MRI using brain extraction software for the model of the brain, and custom code for the model of the skull. The preparation protocol takes advantage of state-of-the-art 3D printing technology to make interfacing brains, skulls, and molds for gel brain models. The skull and brain models can be used to visualize brain tissue inside the skull with the addition of a craniotomy in the custom code, allowing for better preparation for surgeries directly involving the brain. The applications of these methods are designed for surgeries involved in neurological stimulation and recording as well as injection, but the versatility of the system allows for future expansion of the protocol, extraction techniques, and models to a wider scope of surgeries.

Indexed as

AnimalsMagnetic Resonance ImagingNeurosurgeryPrimates

Identifiers

PMID32744531
PMCPMC8384434

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.