ArticleeLife2020
Boosts in brain signal variability track liberal shifts in decision bias.
Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Scale-Dependent Development of Neural Signal Complexity and its Association with Working Memory in Childhood.Brain topography · 2026Article
- Age-Related Changes in EEG Signal Complexity and Behavioral Variability from Childhood to Adulthood: A Multiscale Entropy Approach.Entropy (Basel, Switzerland) · 2026Article
- EEG entropy modulation as a biomarker of emotion regulation and resilience.IBRO neuroscience reports · 2025Review
- Did you see it?eLife · 2025Article
- Brain Complexity and Parametrization of Power Spectral Density in Children with Specific Language Impairment.Entropy (Basel, Switzerland) · 2025Article
- Criterion placement threatens the construct validity of neural measures of consciousness.eLife · 2025Article
- Broadscale dampening of uncertainty adjustment in the aging brain.Nature communications · 2024Article
- From the brain's encoding of input dynamics to its behavior: neural dynamics shape bias in decision making.Communications biology · 2024Article
- Multiscale entropy of ADHD children during resting state condition.Cognitive neurodynamics · 2023Article
- Altered frontal connectivity as a mechanism for executive function deficits in fragile X syndrome.Molecular autism · 2022Article
- Brain entropy, fractal dimensions and predictability: A review of complexity measures for EEG in healthy and neuropsychiatric populations.The European journal of neuroscience · 2022Review
- Thalamocortical excitability modulation guides human perception under uncertainty.Nature communications · 2021Article
- Decision-Making in the Human-Machine Interface.Frontiers in psychology · 2021Article
- Standard multiscale entropy reflects neural dynamics at mismatched temporal scales: What's signal irregularity got to do with it?PLoS computational biology · 2020Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Adopting particular decision biases allows organisms to tailor their choices to environmental demands. For example, a liberal response strategy pays off when target detection is crucial, whereas a conservative strategy is optimal for avoiding false alarms. Using conventional time-frequency analysis of human electroencephalographic (EEG) activity, we previously showed that bias setting entails adjustment of evidence accumulation in sensory regions (Kloosterman et al., 2019), but the presumed prefrontal signature of a conservative-to-liberal bias shift has remained elusive. Here, we show that a liberal bias shift is reflected in a more unconstrained neural regime (boosted entropy) in frontal regions that is suited to the detection of unpredictable events. Overall EEG variation, spectral power and event-related potentials could not explain this relationship, highlighting that moment-to-moment neural variability uniquely tracks bias shifts. Neural variability modulation through prefrontal cortex appears instrumental for permitting an organism to adapt its biases to environmental demands.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.