Evidence map›Paper›PMID 32744258›Full record

ArticleActa crystallographica. Section D, Structural biology2020

Novel structure of the N-terminal helical domain of BibA, a group B streptococcus immunogenic bacterial adhesin.

Kartik Manne, Debasish Chattopadhyay, Vaibhav Agarwal, Anna M Blom, Baldeep Khare, Srinivas Chakravarthy, Chungyu Chang, Hung Ton-That, Sthanam V L Narayana

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta crystallographica. Section D, Structural biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Frontiers in cellular and infection microbiology · 2024
    Article
  4. Article
  5. Article
  6. Characterization and virulence ofFrontiers in microbiology · 2023
    Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Kartik ManneCenter for Biophysical Sciences and Engineering, University of Alabama at Birmingham, Birningham, AL 35294, USA.ORCID 0000-0002-7218-4852
Debasish ChattopadhyayDepartment of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA.ORCID 0000-0001-5262-9140
Vaibhav AgarwalDepartment of Translational Medicine, Lund University, S-214 28 Malmö, Sweden.
Anna M BlomDepartment of Translational Medicine, Lund University, S-214 28 Malmö, Sweden.
Baldeep KhareDepartment of Biological Sciences, Purdue University, West Lafayette, Indiana, USA.ORCID 0000-0002-7415-0058
Srinivas ChakravarthyThe Biophysics Collaborative Access Team (BioCAT), Department of Biological Sciences, Illinois Institute of Technology, Chicago, IL 60616, USA.
Chungyu ChangDivision of Oral Biology and Medicine, School of Dentistry, University of California Los Angeles, Los Angeles, California, USA.
Hung Ton-ThatDivision of Oral Biology and Medicine, School of Dentistry, University of California Los Angeles, Los Angeles, California, USA.
Sthanam V L NarayanaCenter for Biophysical Sciences and Engineering, University of Alabama at Birmingham, Birningham, AL 35294, USA.
University of Alabama at Birmingham · USLund University · SEUniversity of California, Los Angeles · USIllinois Institute of Technology · USPurdue University West Lafayette · US

Funding

Time resolved SAXS studies on the RP2/Arl3 complex pp.484-485P41GM103622 · NIGMS · ILLINOIS INSTITUTE OF TECHNOLOGY · PI IRVING, THOMAS C · 2012 to 2020
$11.9M
Molecular Assembly on the Cell Surface of ActinomycesR01DE017382 · NIDCR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI Hung Ton-That · 2008 to 2026
$6.7M
Post-translocational protein folding in Gram-positive bacteriaR01DE025015 · NIDCR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI TON-THAT, HUNG · 2015 to 2024
$3.9M
Complement Evasion by Group B StreptococcusR01AI106808 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI STHANAM, NARAYANA VL · 2014 to 2017
$1.5M
Advanced Pixel Array Detector for Time-Resolved SAXS and Fiber DiffractionS10OD018090 · OD · ILLINOIS INSTITUTE OF TECHNOLOGY · PI IRVING, THOMAS C · 2014 to 2014
$529k
NIAID NIH HHS R01 AI106808NIDCR NIH HHS R01 DE017382NIDCR NIH HHS R01-DE017382NIDCR NIH HHS R01 DE025015NIDCR NIH HHS R01-DE025015NIGMS NIH HHS P41 GM103622NIH HHS S10 OD018090
6 · The paper itself

Abstract

BibA, a group B streptococcus (GBS) surface protein, has been shown to protect the pathogen from phagocytic killing by sequestering a complement inhibitor: C4b-binding protein (C4BP). Here, the X-ray crystallographic structure of a GBS BibA fragment (BibA

Indexed as

Adhesins, BacterialBinding SitesComplement C4b-Binding ProteinCrystallography, X-RayProtein Conformation, alpha-HelicalStreptococcus agalactiaeAdhesins, BacterialComplement C4b-Binding ProteinBibAC4b-binding proteinsgroup B streptococcusimmunogenic bacterial adhesinsthree-helix-bundle-motif repeats

Identifiers

PMID32744258
PMCPMC7397492
OpenAlexW3045912711

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.