Evidence map›Paper›PMID 32744084›Full record

ArticleAmerican journal of physiology. Renal physiology2020

Sex differences in solute transport along the nephrons: effects of Na

Rui Hu, Alicia A McDonough, Anita T Layton

Open access · hybridAbstract read
In one paragraph

Article in American journal of physiology. Renal physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 72 citations in OpenAlex.

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  16. Circadian gene expression in mouse renal proximal tubule.American journal of physiology. Renal physiology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Rui HuDepartment of Applied Mathematics, University of Waterloo, Waterloo, Ontario, Canada.
Alicia A McDonoughDepartment of Physiology and Neuroscience, Keck School of Medicine, University of Southern California, Los Angeles, California.ORCID 0000-0002-0459-469X
Anita T LaytonDepartment of Applied Mathematics, University of Waterloo, Waterloo, Ontario, Canada.
University of Waterloo · CAUniversity of Southern California · US

Funding

Sodium transporter regulation during hypertensionR01DK083785 · NIDDK · UNIVERSITY OF SOUTHERN CALIFORNIA · PI AURELIE EDWARDS, Alicia A. McDonough · 2011 to 2026
$5.8M
NIDDK NIH HHS R01 DK083785Office of Extramural Research, National Institutes of Health (OER) 2R01DK083785
6 · The paper itself

Abstract

Each day, ~1.7 kg of NaCl and 180 liters of water are reabsorbed by nephron segments in humans, with urinary excretion fine tuned to meet homeostatic requirements. These tasks are coordinated by a spectrum of renal Na

Indexed as

Computer SimulationModels, BiologicalAnimalsBiological TransportFemaleMaleNephronsRatsSex FactorsSodiumSodium Potassium Chloride Symporter InhibitorsSodium-Potassium-Chloride SymportersSodiumSodium Potassium Chloride Symporter InhibitorsSodium-Potassium-Chloride Symportersdiuresisepithelial Na+ channelNa+-Cl− cotransporterNa+/H+ exchanger 3Na+-K+-2Cl− cotransporternatriuresis

Identifiers

PMID32744084
PMCPMC7509281
OpenAlexW3047259774

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.