Evidence map›Paper›PMID 32743851›Full record

ArticleDevelopmental psychobiology2021

The moderating role of externalizing problems on the association between anxiety and the error-related negativity in youth.

Jennifer H Suor, Maria Granros, Autumn Kujawa, Kate D Fitzgerald, Christopher S Monk, K Luan Phan, Katie L Burkhouse

Open access · bronzeAbstract read
In one paragraph

Article in Developmental psychobiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Jennifer H SuorDepartment of Psychiatry, University of Illinois at Chicago, Chicago, IL, USA.ORCID 0000-0003-2626-4402
Maria GranrosDepartment of Psychiatry, University of Illinois at Chicago, Chicago, IL, USA.
Autumn KujawaDepartment of Psychology & Human Development, Vanderbilt University, Nashville, TN, USA.
Kate D FitzgeraldDepartment of Psychiatry, University of Michigan, Ann Arbor, MI, USA.ORCID 0000-0002-6502-7031
Christopher S MonkDepartment of Psychology, University of Michigan, Ann Arbor, MI, USA.
K Luan PhanDepartment of Psychiatry, University of Illinois at Chicago, Chicago, IL, USA.
Katie L BurkhouseDepartment of Psychiatry, University of Illinois at Chicago, Chicago, IL, USA.
University of Illinois Chicago · USUniversity of Michigan · USVanderbilt University · US

Funding

Brain Markers of Anxiety Disorders and SSRI Treatment in Children and AdolescentsR01MH086517 · NIMH · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MONK, CHRISTOPHER STEPHEN, PHAN, K. LUAN · 2010 to 2014
$2.8M
Brain-Behavior Markers of Emotion in Depressed Mothers and Their DaughtersK23MH113793 · NIMH · UNIVERSITY OF ILLINOIS AT CHICAGO · PI BURKHOUSE, KATIE L · 2017 to 2021
$1.0M
Predicting and Preventing High-Risk Adolescent Behavior F32HD100075 · NICHD · UNIVERSITY OF ILLINOIS AT CHICAGO · PI SUOR, JENNIFER · 2019 to 2022
$205k
NICHD NIH HHS F32 HD100075NIMH NIH HHS K23 MH113793NIMH NIH HHS R01 MH086517
6 · The paper itself

Abstract

The error-related negativity (ERN) is an event-related potential that reflects error monitoring. Enhanced ERN indicates sensitivity to performance errors and is a correlate of anxiety disorders. In contrast, youth with externalizing problems exhibit a reduced ERN, suggesting decreased error monitoring. Anxiety and externalizing problems commonly co-occur in youth, but no studies have tested how comorbidity might modulate the ERN. In a sample of youth (N = 46, ages 7-19) with and without anxiety disorders, this preliminary study examined the interactive effect of anxiety and externalizing problems on ERN. Results suggest that externalizing problems moderate the relation between anxiety symptoms and ERN in youth. Anxious youth with less externalizing problems exhibited enhanced ERN response to errors. Conversely, anxious youth with greater externalizing problems demonstrated diminished ERN in response to errors. The regions of significance and proportion affected tests indicated that the moderating the effect of externalizing problems was only significant for youth with anxiety disorders. Findings suggest that enhanced neural error sensitivity could be a specific neurophysiological marker for anxiety disorders, whereas anxious individuals with comorbid externalizing problems demonstrate reduced error monitoring, similar to those with primary externalizing pathology. Results underscore the utility of examining neural correlates of pediatric anxiety comorbidity subtypes.

Indexed as

Anxiety DisordersElectroencephalographyAdolescentAdultAnxietyChildEvoked PotentialsHumansYoung Adultanxietyerror-related negativityexternalizing behaviors

Identifiers

PMID32743851
PMCPMC7855835
OpenAlexW3047383190

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.