ArticleInfection2021
Early-onset symptomatic neonatal COVID-19 infection with high probability of vertical transmission.
Article in Infection, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 4 of them syntheses that pooled it.
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Who cites it
31 citing papers in PubMed, 4 syntheses or guidelines pooled it, 47 citations in OpenAlex.
- COVID-19 in Neonates with Positive RT-PCR Test. Systematic Review.Archives of medical research · 2022Pooled it
- The Spectrum of Antibiotic Prescribing During COVID-19 Pandemic: A Systematic Literature Review.Microbial drug resistance (Larchmont, N.Y.) · 2021Pooled it
- Synthesis and systematic review of reported neonatal SARS-CoV-2 infections.Nature communications · 2020Pooled it
- COVID-19 in pregnancy: the foetal perspective-a systematic review.BMJ paediatrics open · 2020Pooled it
- Maternal COVID-19 exposure and placental characteristics.PloS one · 2024Article
- Method Validation Study for SARS-CoV-2 Viral RNA Detection in Cervical, Rectal, Amniotic Fluid, Placental, Umbilical Cord Blood, and Breastmilk Specimens in a Cohort of Unvaccinated Women in Manila, Philippines.Acta medica Philippina · 2024Article
- A multicentre study on the clinical characteristics of newborns infected with coronavirus disease 2019 during the omicron wave.Frontiers in pediatrics · 2023Article
- In-utero transmission of SARS CoV-2 infection during delta variant outbreak: first Australian experience.Infection · 2022Article
- Clinical Profile of SARS-CoV-2-Infected Neonates.Cureus · 2022Article
- SARS-CoV-2 Infection and Possible Neonatal Neurological Outcomes: A Literature Review.Viruses · 2022Review
- The youngest surviving COVID-19 patient: A case report.International journal of surgery case reports · 2022Article
- Management of severe neonatal respiratory distress due to vertical transmission of severe acute respiratory syndrome coronavirus 2: a case report.Journal of medical case reports · 2022Article
- Clinical Outcome of Neonates Born to SARS-CoV-2 Positive Mothers in India: A Systematic Review and Meta-Analysis.Cureus · 2022Review
- Prenatal and neonatal complications of COVID-19: A systematic review.Health science reports · 2022Review
- The Impact of the SARS-CoV-2 Pandemic on Reproduction, Sexual Function and Behaviors: A Review of the Main Trends and Findings.International journal of sexual health : official journal of the World Association for Sexual Health · 2022Article
- Intrauterine Vertical Transmission of SARS-CoV-2 Infection Among Confirmed Cases of Pregnant Women: "A Double Burden for the Pregnant Women"-A Systematic Review.Global pediatric health · 2022Review
- Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Pregnancy. A Non-systematic Review of Clinical Presentation, Potential Effects of Physiological Adaptations in Pregnancy, and Placental Vascular Alterations.Frontiers in physiology · 2022Review
- Effects of COVID-19 and mRNA vaccines on human fertility.Human reproduction (Oxford, England) · 2021Article
- Probable vertical transmission of severe acute respiratory syndrome coronavirus 2 infection from mother to neonate.Medical journal, Armed Forces India · 2021Article
- A single-center observational study on clinical features and outcomes of 21 SARS-CoV-2-infected neonates from India.European journal of pediatrics · 2021Observational
Corrections and comments
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Authors and funding
15 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere are few reports of COVID-19 in neonates and most are suspected to be due to postnatal transmission. Vertical transmission has been proven in only a couple of cases so far.
methodsWe describe early-onset, severe COVID-19 disease in a neonate with very strong evidence of vertical transmission of SARS-CoV-2.
resultsA COVID-19 suspected mother, who tested negative by RT-PCR for COVID, but tested positive for SARS-CoV-2 by serology, delivered a term baby. The neonate was kept in strict isolation. Molecular tests for SARS-CoV-2 on umbilical stump, placenta, and nasopharyngeal aspirate of the neonate, collected at birth were positive. On day 2, the neonate developed clinical features of COVID in the form of fever, poor feeding, and hyperbilirubenemia along with elevated inflammatory markers. Antibiotics were started empirically pending cultures. Blood, CSF, and urine cultures were sterile. Baby tested RT-PCR positive for SARS-CoV-2 on two more occasions before testing positive for antibodies and was discharged on day 21 of life.
conclusionThis report highlights a very strong possibility of vertical transmission of COVID-19 from a mildly symptomatic, RT-PCR negative but antibody-positive mother with significant symptomatic, early-onset neonatal infection.
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