Evidence map›Paper›PMID 32743577›Full record

ArticlebioRxiv : the preprint server for biology2020

Interferons and viruses induce a novel primate-specific isoform dACE2 and not the SARS-CoV-2 receptor ACE2.

Olusegun O Onabajo, A Rouf Banday, Wusheng Yan, Adeola Obajemu, Megan L Stanifer, Deanna M Santer, Oscar Florez-Vargas, Helen Piontkivska, Joselin Vargas, Carmon Kee and 4 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 25 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 3 countries.

Olusegun O OnabajoLaboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
A Rouf BandayLaboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Wusheng YanLaboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Adeola ObajemuLaboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Megan L StaniferDepartment of Infectious Diseases, Molecular Virology, University Hospital Heidelberg, Heidelberg, Germany.
Deanna M SanterLi Ka Shing Institute of Virology and Department of Medical Microbiology and Immunology, University of Alberta, Edmonton, Alberta, Canada.
Oscar Florez-VargasLaboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Helen PiontkivskaDepartment of Biological Sciences and Brain Health Research Institute, Kent State University, Kent, OH, USA.
Joselin VargasLaboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Carmon KeeDivision of Cellular Polarity and Viral Infection, German Cancer Research Center (DKFZ), Heidelberg, Germany.
D Lorne J TyrrellLi Ka Shing Institute of Virology and Department of Medical Microbiology and Immunology, University of Alberta, Edmonton, Alberta, Canada.
Juan L MendozaPritzker School of Molecular Engineering and Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, IL, USA.
Steeve BoulantDivision of Cellular Polarity and Viral Infection, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Ludmila Prokunina-OlssonLaboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
National Institutes of Health · USGerman Cancer Research Center · DEUniversity of Alberta · CAHeidelberg University · DEKent State University · USUniversity of Chicago · US

Funding

Characterization of transcriptome changes in diet-induced progression to METS/T2D to identify earliest and sex-specific neurodegenerative foci for AD developmentR21AG064479 · NIA · UNIVERSITY OF FLORIDA · PI CASADESUS, GEMMA · 2019 to 2020
$598k
NIA NIH HHS R21 AG064479
6 · The paper itself

Abstract

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), which causes COVID-19, utilizes angiotensin-converting enzyme 2 (ACE2) for entry into target cells.

Indexed as

ACE2COVID-19immune responseInterferonInterferon-stimulated geneSARS-CoV-2

Identifiers

PMID32743577
PMCPMC7386494
OpenAlexW3042768584

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.