Evidence map›Paper›PMID 32743518›Full record

ArticleJournal of translational autoimmunity2020

A patient with primary biliary cholangitis, autoimmune hepatitis, and primary sclerosing cholangitis variant syndrome.

Benedetta Terziroli Beretta-Piccoli, Luca Mazzucchelli, Chiara Taiana, Giuseppe Mossi, Corrado Usai, Diego Vergani, Giorgina Mieli-Vergani

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of translational autoimmunity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Benedetta Terziroli Beretta-PiccoliEpatocentro Ticino, Lugano, Switzerland.
Luca MazzucchelliCantonal Pathology Institute, Locarno, Switzerland.
Chiara TaianaStudio Medico, Canobbio, Switzerland.
Giuseppe MossiStudio Medico, Maggia, Switzerland.
Corrado UsaiRadiology Department, Regional Hospital EOC, Locarno, Switzerland.
Diego VerganiInstitute of Liver Studies, MowatLabs, King's College Hospital, London, UK.
Giorgina Mieli-VerganiPaediatric Liver, GI and Nutrition Centre, MowatLabs, King's College Hospital, London, UK.
King's College Hospital · GBEnte Ospedaliero Cantonale · CHEpatocentro Ticino · CHIstituto Cantonale di Patologia · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Overlap between autoimmune hepatitis (AIH) and either primary biliary cholangitis (PBC) or primary sclerosing cholangitis (PSC) is not rare and has extensively been reported. We herein report the first well documented case of triple overlap. A 68-year-old male patient presented with asymptomatic PBC including normal alkaline phosphatase serum level, developed AIH five years later, associated with magnetic resonance cholangiopancreatography biliary changes typical for PSC. Despite treatment with ursodeoxycholic acid and mycophenolate mofetil, owing to prednisone and azathioprine intolerance, he continued to have interface hepatitis and developed increasing fibrosis at follow-up liver biopsy. Our case report raises awareness for this rare and difficult to diagnose and treat clinical phenotype.

Indexed as

Autoimmune hepatitisNormal serum alkaline phosphatase levelPrimary biliary cholangitisPrimary sclerosing cholangitisVariant syndrome

Identifiers

PMID32743518
PMCPMC7388380
OpenAlexW2994843904

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.