Evidence map›Paper›PMID 32743452›Full record

ArticleIJU case reports2019

Syndrome of inappropriate antidiuretic hormone secretion as a side effect of chemotherapy for testicular cancer: A case report.

Koki Maeda, Susumu Kageyama, Takashi Osafune, Yoshikata Masuda, Shota Nakagawa, Kenji Miki, Shun Esumi, Maiko Kakita-Kobayashi, Tetsuya Yoshida, Mitsuhiro Narita and 1 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in IJU case reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Koki MaedaDepartment of Urology Uji-Tokushukai Medical Center Uji Kyoto Japan.ORCID https://orcid.org/0000-0001-5747-6921
Susumu KageyamaDepartment of Urology Shiga University of Medical Science Otsu Shiga Japan.ORCID https://orcid.org/0000-0001-7150-647X
Takashi OsafuneDepartment of Urology Uji-Tokushukai Medical Center Uji Kyoto Japan.
Yoshikata MasudaDepartment of Urology Uji-Tokushukai Medical Center Uji Kyoto Japan.
Shota NakagawaDepartment of Urology Uji-Tokushukai Medical Center Uji Kyoto Japan.
Kenji MikiDepartment of Emergency and General Medicine Uji-Tokushukai Medical Center Uji Kyoto Japan.
Shun EsumiDepartment of Emergency and General Medicine Uji-Tokushukai Medical Center Uji Kyoto Japan.
Maiko Kakita-KobayashiDepartment of Endocrinology and Metabolism Uji-Tokushukai Medical Center Uji Kyoto Japan.
Tetsuya YoshidaDepartment of Urology Shiga University of Medical Science Otsu Shiga Japan.
Mitsuhiro NaritaDepartment of Urology Shiga University of Medical Science Otsu Shiga Japan.
Akihiro KawauchiDepartment of Urology Shiga University of Medical Science Otsu Shiga Japan.
Fukuoka Tokushukai Hospital · JPShiga University of Medical Science · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionInappropriate antidiuretic hormone secretion syndrome can be a serious adverse event of cisplatin-based chemotherapy. Cisplatin had to be changed to other drugs or chemotherapy completely discontinued in earlier reported cases. CASE PRESENTATION: Three cycles of bleomycin, etoposide, and cisplatin chemotherapy were planned for a 40-year-old man with a diagnosis of lymph node recurrence of testicular cancer. On day 9, he suffered from vomiting and mental disturbance. Severe hyponatremia (110 mEq/L) with low plasma osmolality led to a diagnosis of a syndrome of inappropriate antidiuretic hormone secretion, and infusions of hypertonic saline and salt intake were prescribed. Second and third courses of bleomycin, etoposide, and cisplatin chemotherapy could then be given with careful electrolyte management.

conclusionContinuation of cisplatin administration with precise electrolyte adjustment can be a treatment option in regimens where cisplatin is essential for achieving optimal antitumor efficacy.

Indexed as

chemotherapyhyponatremiarenal salt wasting syndromesyndrome of inappropriate antidiuretic hormone secretiontesticular cancer

Identifiers

PMID32743452
PMCPMC7292171
OpenAlexW2979499495

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.