Evidence map›Paper›PMID 32743423›Full record

ArticleIJU case reports2019

Rare case of Richter syndrome with testicular involvement successfully obtained good prognosis with rapid operation and immunochemotherapy.

Kengo Kawase, Taku Naiki, Aya Naiki-Ito, Masamitsu Yanada, Yosuke Ikegami, Yuya Ota, Tatsuya Hattori, Nayuka Matsuyama, Takashi Hamakawa, Tetsuji Maruyama and 1 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in IJU case reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Chronic lymphocytic leukemia and concurrent seminoma in the same testis.Journal of pathology and translational medicine · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Kengo KawaseDepartment of Nephro-Urology Graduate School of Medical Sciences Nagoya City University Nagoya Aichi Japan.
Taku NaikiDepartment of Nephro-Urology Graduate School of Medical Sciences Nagoya City University Nagoya Aichi Japan.ORCID https://orcid.org/0000-0002-7638-6048
Aya Naiki-ItoPathology Division Nagoya City East Medical Center Nagoya Aichi Japan.
Masamitsu YanadaDepartment of Hematology and Cell Therapy Aichi Cancer Center Nagoya Aichi Japan.
Yosuke IkegamiDepartment of Urology Nagoya City East Medical Center Nagoya Aichi Japan.
Yuya OtaDepartment of Nephro-Urology Graduate School of Medical Sciences Nagoya City University Nagoya Aichi Japan.
Tatsuya HattoriDepartment of Urology Nagoya City East Medical Center Nagoya Aichi Japan.
Nayuka MatsuyamaDepartment of Urology Nagoya City East Medical Center Nagoya Aichi Japan.
Takashi HamakawaDepartment of Urology Nagoya City East Medical Center Nagoya Aichi Japan.
Tetsuji MaruyamaDepartment of Urology Nagoya City East Medical Center Nagoya Aichi Japan.
Takahiro YasuiDepartment of Nephro-Urology Graduate School of Medical Sciences Nagoya City University Nagoya Aichi Japan.
Nagoya Medical Center · JPNagoya City University · JPAichi Cancer Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionRichter syndrome refers to the transformation from chronic lymphocytic leukemia to assaultive lymphoma, often a diffuse large B-cell lymphoma, and has a greatly poor prognosis. Richter syndrome is characterized by rapidly growing lymphadenopathy but rarely presents with extra-nodal involvement, common sites being the digestive tract, lungs, kidneys, and central nervous system. However, Richter syndrome with testicular involvement is extremely rare. CASE PRESENTATION: Herein we report a very scare case of a male at the age of 72 with Richter syndrome and testicular involvement, diagnosed by the investigation of bilateral scrotal swellings. The patient had attained disease-free survival for over a year with rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone, and the intrathecal administration of chemotherapeutic agents after diagnosis by immediate orchiectomy.

conclusionAn early pathological diagnosis by immediate orchiectomy and the early initiation of induction immunochemotherapy may be good prognostic factors in Richter syndrome involving the testes.

Indexed as

CLL/SLLdiffuse large B‐cell lymphomaRichter syndrometesticular germ cell tumor

Identifiers

PMID32743423
PMCPMC7292090
OpenAlexW2951463033

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.