Evidence map›Paper›PMID 32743374›Full record

ArticleIJU case reports2019

Neoadjuvant chemotherapy for high-risk prostatic adenocarcinoma.

Robert Brunner, Bradley Buck, Zane Giffen, Daniel Murtagh, Terrence Lewis, Cara Gatto-Weis, Puneet Sindhwani

Open access · goldAbstract readCase Reports
In one paragraph

Article in IJU case reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 99% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Image-Guided Precision Treatments.Advances in experimental medicine and biology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Robert BrunnerDepartment of Urology College of Medicine and Life Sciences The University of Toledo Toledo Ohio USA.ORCID 0000-0002-8490-6162
Bradley BuckDepartment of Urology College of Medicine and Life Sciences The University of Toledo Toledo Ohio USA.
Zane GiffenDepartment of Urology College of Medicine and Life Sciences The University of Toledo Toledo Ohio USA.
Daniel MurtaghDepartment of Urology College of Medicine and Life Sciences The University of Toledo Toledo Ohio USA.
Terrence LewisDepartment of Radiology College of Medicine and Life Sciences The University of Toledo Toledo Ohio USA.
Cara Gatto-WeisDepartment of Pathology College of Medicine and Life Sciences The University of Toledo Toledo Ohio USA.
Puneet SindhwaniDepartment of Urology College of Medicine and Life Sciences The University of Toledo Toledo Ohio USA.
University of Toledo · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionNeoadjuvant chemotherapy in high-risk, locally advanced prostate cancer remains an understudied area of prostate cancer. Chemotherapy continues to be a viable option. The combination with surgery may be desired but lacks data for complete recommendation. CASE PRESENTATION: We demonstrate the successful utilization of chemotherapy in the neoadjuvant arena. A 70-year-old male was diagnosed with high-risk prostate cancer on biopsy. Upon multiparametric magnetic resonance imaging, the patient had local rectal wall invasion and stage T4 N0 M0 after a negative bone scan. After treatment with androgen-deprivation therapy and docetaxel, repeat multiparametric magnetic resonance imaging showed regression of rectal invasion. The patient elected for prostatectomy and avoided proctectomy and colostomy. The patient's postoperative prostate-specific antigen was undetectable on initial follow-up.

conclusionWe show that neoadjuvant chemotherapy merits further study and may provide a more permanent surgical option for patients.

Indexed as

docetaxelneoadjuvant chemotherapyprostate cancerprostatectomyprostatic adenocarcinoma

Identifiers

PMID32743374
PMCPMC7292178
OpenAlexW2911759628

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.