Evidence map›Paper›PMID 32743361›Full record

ArticleIJU case reports2019

Enzalutamide-induced severe thrombocytopenia complicated by a seizure in a 76-year-old man with castration-resistant prostate cancer.

Masaki Murata, Itsuhiro Takizawa, Ryo Maruyama, Takashi Kasahara, Noboru Hara, Yoshihiko Tomita

Open access · goldAbstract readCase Reports
In one paragraph

Article in IJU case reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Masaki MurataDivision of Urology Department of Regenerative and Transplant Medicine Graduate School of Medical and Dental Sciences Niigata University Niigata Japan.
Itsuhiro TakizawaDivision of Urology Department of Regenerative and Transplant Medicine Graduate School of Medical and Dental Sciences Niigata University Niigata Japan.
Ryo MaruyamaDivision of Urology Department of Regenerative and Transplant Medicine Graduate School of Medical and Dental Sciences Niigata University Niigata Japan.
Takashi KasaharaDivision of Urology Department of Regenerative and Transplant Medicine Graduate School of Medical and Dental Sciences Niigata University Niigata Japan.
Noboru HaraDivision of Urology Department of Regenerative and Transplant Medicine Graduate School of Medical and Dental Sciences Niigata University Niigata Japan.ORCID 0000-0003-3985-0603
Yoshihiko TomitaDivision of Urology Department of Regenerative and Transplant Medicine Graduate School of Medical and Dental Sciences Niigata University Niigata Japan.
Niigata University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAdverse events with enzalutamide widely used for men with castration-resistant prostate cancer are of interest. CASE PRESENTATION: A 76-year-old man developed castration-resistant prostate cancer. He received 160 mg of enzalutamide daily. On the 13th day after treatment, severe thrombocytopenia was observed (platelet count: 1.9 × 10

conclusionThrombocytopenia may occur early following enzalutamide therapy, and blood analysis within 2 weeks after treatment may facilitate its management. Enzalutamide-induced thrombocytopenia, complicated by seizure, has not been reported.

Indexed as

castration‐resistant prostate cancerenzalutamideseizuresevere adverse eventthrombocytopenia

Identifiers

PMID32743361
PMCPMC7292079
OpenAlexW2898700324

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.