Evidence map›Paper›PMID 32743107›Full record

ArticleHeliyon2020

Autopsy of 54 cases of surgically excised cardiac myxomas. Investigation of their impact on immune response.

Nektaria Michopanou, Nikolaos Schizas, Christos Charitos, Demetra Rontogianni, George Saroglou, Alkiviadis Vatopoulos, Rokeia Eltheni, Ioanna Pavlopoulou

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Nektaria MichopanouCardiac Surgery Intensive Care Unit, Evangelismos General Hospital, 45-47 Ipsilantou Street, 10676, Athens, Greece.
Nikolaos SchizasCardiac Surgery Intensive Care Unit, Evangelismos General Hospital, 45-47 Ipsilantou Street, 10676, Athens, Greece.
Christos CharitosCardiothoracic Surgery Department, Evangelismos General Hospital, 45-47 Ipsilantou Street, 10676, Athens, Greece.
Demetra RontogianniPathology Department, Evangelismos General Hospital, 45-47 Ipsilantou Street, 10676, Athens, Greece.
George SaroglouFaculty of Nursing, School of Healthcare Sciences, National and Kapodistrian University of Athens, 123 Papadiamantopoulou street, 11527, Athens, Greece.
Alkiviadis VatopoulosFaculty of Public Health, University of West Attica, 28 Agiou Spyridonos street, Egaleo, 12243, Athens, Greece.
Rokeia EltheniCardiac Surgery Intensive Care Unit, Evangelismos General Hospital, 45-47 Ipsilantou Street, 10676, Athens, Greece.
Ioanna PavlopoulouFaculty of Public Health, University of West Attica, 28 Agiou Spyridonos street, Egaleo, 12243, Athens, Greece.
Evangelismos Hospital · GRUniversity of West Attica · GRNational and Kapodistrian University of Athens · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe impact of cardiac myxomas on the immune response is still indefinite, although laboratory tests and histological findings suggest that there is a correlation between myxomas and inflammatory reaction.

objectivesOur study speculates that cardiac myxomas are associated with inflammatory response and investigates potential elements of inflammation in the histopathological examination and biomarkers from laboratory tests.

methodsIt is a retrospective study and data were collected from a single center between May 2010 to May 2018. Autopsies and laboratory tests of 54 cases were analyzed.

resultsIn 20,4% of the autopsies, inflammatory elements were identified. The neutrophil/lymphocyte ratio (NLR) preoperatively is elevated in patients suffering from cardiac myxoma while its value is correlated to the tumor size.

conclusionsCardiac myxoma is an entity that affects the immune response of patients. The biomarker NLR could be utilized as a prognostic factor regarding enlarged cardiac myxomas. Future studies still need to be conducted in order to confirm the usefulness of this biomarker on cardiac myxomas.

Indexed as

BiomarkerCardiac myxomaCardiologyImmunologyInflammatory responseNeutrophil/lymphocyte ratioNLRPathologyPathophysiology

Identifiers

PMID32743107
PMCPMC7385451
OpenAlexW3043829469

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.