ReviewGlobal pediatric health2020
Magnitude and Associated Factors of Neural Tube Defects in Ethiopia: A Systematic Review and Meta-Analysis.
Review in Global pediatric health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 6 of them syntheses that pooled it.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
39 citing papers in PubMed, 6 syntheses or guidelines pooled it, 55 citations in OpenAlex.
- Folate and global health umbrella review series, part 1: methodological framework and syntheses on anaemia and neural tube defects.Journal of global health · 2026Pooled it
- Birth prevalence and determinants of neural tube defects among newborns in Ethiopia: A systematic review and meta-analysis.PloS one · 2025Pooled it
- Birth prevalence and risk factors of neural tube defects in Ethiopia: a systematic review and meta-analysis.BMJ open · 2023Pooled it
- Folate deficiency among women of reproductive age in Ethiopia: A systematic review and meta-analysis.PloS one · 2023Pooled it
- Global prevalence of congenital anencephaly: a comprehensive systematic review and meta-analysis.Reproductive health · 2022Pooled it
- Knowledge of preconception care and its association with family planning utilization among women in Ethiopia: meta-analysis.Scientific reports · 2021Pooled it
- Effect of nutrition intervention coupled with healthy dietary advice on the nutritional status of pregnant women in the northern zone of the Sidama region, Ethiopia: a multilevel, cluster randomized controlled trial.Journal of health, population, and nutrition · 2025Trial
- EAU-ESPU-ERN eUROGEN-ERN ITHACA-ERN ERKNet-IFSBH Guidelines on Spinal Dysraphism in Children and Adolescents: Summary of the Guideline.European urology open science · 2026Article
- MaternalGenes · 2026Article
- The prevalence of neural tube defects in eastern Ethiopia: A population-based surveillance.PLOS global public health · 2026Article
- Preconception Care and Genetic Screening: A Global Review and Strategic Perspectives for Implementation in Bulgaria.Children (Basel, Switzerland) · 2025Review
- Inadequate Status of Multiple B Vitamins is Common Among Women in Oromia Region, Ethiopia.Current developments in nutrition · 2025Article
- The Cost of Expanding Ethiopia's Salt Iodization Program to Include Multiple Micronutrients.Current developments in nutrition · 2025Article
- Assessment of Women's Discretionary Salt Intake and Household Salt Utilization in Preparation for a Salt Fortification Trial in Oromia Region, Ethiopia.Maternal & child nutrition · 2025Article
- Prenatal ultrasound utilization and associated factors among pregnant women attending antenatal care in south Wollo zone public hospitals, north east, Ethiopia, 2023.Frontiers in digital health · 2025Article
- Double Fortified Salt Containing Iodine and Folic Acid and Triple Fortified Salt Containing Iodine, Folic Acid, and Vitamin BFood science & nutrition · 2025Article
- National strategies for screening neural tube defects in Saudi Arabia: activating prevention and early intervention.Frontiers in public health · 2025Review
- Neural tube defect among newborns in public hospitals of Tigray region, northern Ethiopia: A cross-sectional study.PloS one · 2025Article
- Are congenital malformations associated with maternal sociodemographic and risk factors? A multicenter ultrasound-based study.Pakistan journal of medical sciences · 2024Article
- Article
Corrections and comments
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Authors and funding
4 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Neural tube defects remain a major problem in developing countries, but there are limited comprehensive national reports to date in Ethiopia. Therefore, this study aimed to assess the prevalence of neural tube defects and associated factors in Ethiopia. Electronic databases and other sources were used to retrieve studies. Fifteen out of 862 studies were included in the final analysis. The estimated pooled prevalence of neural tube defects among children in Ethiopia was 63.3 cases per 10 000 children. The pooled prevalence of spinal bifida, anencephaly, and encephalocele was 41.09, 18.90, and 1.07 per 10 000 children, respectively. Previous family history and unplanned pregnancy were risk factors for neural tube defects. Folic acid supplementation during the first trimester of pregnancy was found to be protective. Neural tube defects are widespread in Ethiopia. Hence, fortification of food with folic acid or folic acid supplementation during childbearing age is recommended.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.