ArticleOpen forum infectious diseases2020
Clinical Manifestation and Neonatal Outcomes of Pregnant Patients With Coronavirus Disease 2019 Pneumonia in Wuhan, China.
Article in Open forum infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 6 of them syntheses that pooled it.
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Who cites it
23 citing papers in PubMed, 6 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- A snapshot of the prevalence of endocrine disorders in pregnancies complicated by coronavirus disease 2019: A narrative review with meta-analysis.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2021Pooled it
- COVID-19 in pregnancy: a systematic review of chest CT findings and associated clinical features in 427 patients.Clinical imaging · 2021Pooled it
- The Differences in Clinical Presentation, Management, and Prognosis of Laboratory-Confirmed COVID-19 between Pregnant and Non-Pregnant Women: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2021Pooled it
- Current trends and geographical differences in therapeutic profile and outcomes of COVID-19 among pregnant women - a systematic review and meta-analysis.BMC pregnancy and childbirth · 2021Pooled it
- Prevalence and outcomes of co-infection and superinfection with SARS-CoV-2 and other pathogens: A systematic review and meta-analysis.PloS one · 2021Pooled it
- Clinical manifestations, risk factors, and maternal and perinatal outcomes of coronavirus disease 2019 in pregnancy: living systematic review and meta-analysis.BMJ (Clinical research ed.) · 2020Pooled it
- Outcomes of pregnant ICU patients with severe COVID-19 pneumonia in Qatar during the three waves of the COVID-19 pandemic: A retrospective cohort study.Qatar medical journal · 2025Article
- Comparative analysis of COVID-19 pneumonia in pregnant versus matched non-pregnant women: radiologic, laboratory, and clinical perspectives.Scientific reports · 2024Article
- Reduced control of SARS-CoV-2 infection associates with lower mucosal antibody responses in pregnancy.mSphere · 2024Observational
- Global prevalence of infections in newborns with respiratory complications: systematic review and meta-analysis.Iranian journal of microbiology · 2024Article
- Analysis of pregnant women with critically severe COVID-19 in Republic of Korea from February 2020 and December 2021.Osong public health and research perspectives · 2023Article
- Vaccination options for pregnant women during the Omicron period.Journal of reproductive immunology · 2023Review
- Association of Pregnancy With Coronavirus Cytokine Storm: Systematic Review and Meta-analysis.JMIR pediatrics and parenting · 2022Review
- Impact of SARS-CoV-2 infection on risk of prematurity, birthweight and obstetric complications: A multivariate analysis from a nationwide, population-based retrospective cohort study.BJOG : an international journal of obstetrics and gynaecology · 2022Article
- Trends of Myocarditis and Endocarditis Cases before, during, and after the First Complete COVID-19-Related Lockdown in 2020 in France.Biomedicines · 2022Article
- Characteristics and Outcomes of COVID-19 in Reproductive-Aged Pregnant and Nonpregnant Women in Osaka, Japan.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2022Article
- The perinatal health challenges of emerging and re-emerging infectious diseases: A narrative review.Frontiers in public health · 2022Review
- Pregnancy alters interleukin-1 beta expression and antiviral antibody responses during severe acute respiratory syndrome coronavirus 2 infection.American journal of obstetrics and gynecology · 2021Article
- Review
- SARS-CoV-2-Morphology, Transmission and Diagnosis during Pandemic, Review with Element of Meta-Analysis.Journal of clinical medicine · 2021Review
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Authors and funding
15 authors at 7 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundClinical manifestation and neonatal outcomes of pregnant women with coronavirus disease 2019 (COVID-19) were unclear in Wuhan, China.
methodsWe retrospectively analyzed clinical characteristics of pregnant and nonpregnant women with COVID-19 aged from 20 to 40, admitted between January 15 and March 15, 2020 at Union Hospital, Wuhan, and symptoms of pregnant women with COVID-19 and compared the clinical characteristics and symptoms to historic data previously reported for H1N1.
resultsAmong 64 patients, 34 (53.13%) were pregnant, with higher proportion of exposure history (29.41% vs 6.67%) and more pulmonary infiltration on computed tomography test (50% vs 10%) compared to nonpregnant women. Of pregnant patients, 27 (79.41%) completed pregnancy, 5 (14.71%) had natural delivery, 18 (52.94%) had cesarean section, and 4 (11.76%) had abortion; 5 (14.71%) patients were asymptomatic. All 23 newborns had negative reverse-transcription polymerase chain results, and an average 1-minute Apgar score was 8-9 points. Pregnant and nonpregnant patients show differences in symptoms such as fever, expectoration, and fatigue and on laboratory tests such as neurophils, fibrinogen, D-dimer, and erythrocyte sedimentation rate. Pregnant patients with COVID-19 tend to have more milder symptoms than those with H1N1.
conclusionsClinical characteristics of pregnant patients with COVID-19 are less serious than nonpregnant. No evidence indicated that pregnant women may have fetal infection through vertical transmission of COVID-19. Pregnant patients with H1N1 had more serious condition than those with COVID-19.
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