Evidence map›Paper›PMID 32743007›Full record

ArticleERJ open research2020

Transbronchial cryobiopsy: an effective tool in the diagnosis of lymphoproliferative disorders of the lung.

Rita Bianchi, Alessandra Dubini, Silvia Asioli, Claudia Ravaglia, Sara Tomassetti, Silvia Puglisi, Sara Piciucchi, Christian Gurioli, Carlo Gurioli, Roberto Fiocca and 1 more

Abstract read
In one paragraph

Article in ERJ open research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. Cryobiopsy forRespirology case reports · 2022
    Article
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Rita BianchiDept of Pathology, Università di Genova, Ospedale Policlinico San Martino, Genoa, Italy.
Alessandra DubiniDept of Pathology, Ospedale GB Morgagni, Forlì, Italy.
Silvia AsioliDept of Pathology, Ospedale GB Morgagni, Forlì, Italy.
Claudia RavagliaDept of Diseases of the Thorax, Ospedale GB Morgagni, Forlì, Italy.
Sara TomassettiDept of Diseases of the Thorax, Ospedale GB Morgagni, Forlì, Italy.
Silvia PuglisiDept of Diseases of the Thorax, Ospedale GB Morgagni, Forlì, Italy.
Sara PiciucchiDept of Radiology, Ospedale GB Morgagni, Forlì, Italy.ORCID https://orcid.org/0000-0001-6608-0574
Christian GurioliDept of Diseases of the Thorax, Ospedale GB Morgagni, Forlì, Italy.
Carlo GurioliDept of Diseases of the Thorax, Ospedale GB Morgagni, Forlì, Italy.
Roberto FioccaDept of Pathology, Università di Genova, Ospedale Policlinico San Martino, Genoa, Italy.
Venerino PolettiDept of Diseases of the Thorax, Ospedale GB Morgagni, Forlì, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionMalignant lymphoproliferative disorders are rarely observed in the lung and, considering their clinical and radiological heterogeneity, diagnosis is often difficult and may require invasive methods. Transbronchial cryobiopsy has been confirmed as a new tool in the diagnosis of interstitial lung diseases, given its fewer risks and costs compared to surgical approach. This study is aimed at assessing the effectiveness of cryobiopsy in the diagnosis of lymphoproliferative disorders. MATERIALS AND

methodsAmong 970 consecutive cryobiopsies, performed between January 2011 and June 2018 at Morgagni Hospital of Forlì, Italy, 13 cases of lymphoproliferative disorders were collected.

resultsIn 12 out of 13 cases a precise pathological diagnosis could be reached with the support of immunohistochemistry (IHC) and molecular ancillary studies. In the only case in which cryobiopsy did not lead to a definitive diagnosis, the subsequent surgical biopsy also did not help to clarify the diagnosis. Severe bleeding or pneumothorax did not occur in any case. On average, five biopsies were obtained per case, with a mean total area of 1161 mm

conclusionsTransbronchial lung cryobiopsy is safe and effective for diagnosis in patients with suspected pulmonary involvement by lymphoproliferative disorders and it should therefore be considered a valid alternative to surgical biopsy in such cases.

Identifiers

PMID32743007
PMCPMC7383053

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.