ArticleMicrobial cell (Graz, Austria)2020
Lipid droplet biogenesis from specialized ER subdomains.
Article in Microbial cell (Graz, Austria), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed, 24 citations in OpenAlex.
- The jojoba lipid droplet protein LDAP1 facilitates the packaging of wax esters into lipid droplets.The Plant cell · 2025Article
- Phosphatidic acid drives spatiotemporal distribution of Pex30 at ER-LD contact sites.The Journal of cell biology · 2025Article
- Essential Biology of Lipid Droplets.Annual review of biochemistry · 2025Review
- Omics Approaches to Study Perilipins and Their Significant Biological Role in Cardiometabolic Disorders.International journal of molecular sciences · 2025Review
- A fluorogenic complementation tool kit for interrogating lipid droplet-organelle interaction.The Journal of cell biology · 2024Article
- A unifying mechanism for seipin-mediated lipid droplet formation.FEBS letters · 2024Review
- The evolving landscape of ER-LD contact sites.Frontiers in cell and developmental biology · 2024Review
- Quantifying yeast lipidomics by high-performance thin-layer chromatography (HPTLC) and comparison to mass spectrometry-based shotgun lipidomics.Microbial cell (Graz, Austria) · 2024Article
- Nitrogen limitation-induced adaptive response and lipogenesis in the Antarctic yeastFrontiers in microbiology · 2024Article
- A dynamic actin cytoskeleton is required to prevent constitutive VDAC-dependent MAPK signalling and aberrant lipid homeostasis.iScience · 2023Article
- Glycerolipid Synthesis and Lipid Droplet Formation in the Endoplasmic Reticulum.Cold Spring Harbor perspectives in biology · 2023Review
- Metabolic engineering strategies for de novo biosynthesis of sterols and steroids in yeast.Bioresources and bioprocessing · 2021Review
- Sterols are required for the coordinated assembly of lipid droplets in developing seeds.Nature communications · 2021Article
- Anhydrobiosis in yeast: role of cortical endoplasmic reticulum protein Ist2 in Saccharomyces cerevisiae cells during dehydration and subsequent rehydration.Antonie van Leeuwenhoek · 2021Article
- Actin cytoskeletal inhibitor 19,20-epoxycytochalasin Q sensitizes yeast cells lacking ERG6 through actin-targeting and secondarily through disruption of lipid homeostasis.Scientific reports · 2021Article
- Celia's Encephalopathy (Journal of clinical medicine · 2021Review
- A Unique Junctional Interface at Contact Sites Between the Endoplasmic Reticulum and Lipid Droplets.Frontiers in cell and developmental biology · 2021Review
- Artificial ER-Mitochondrion Tethering Restores Erg6 Localization and Lipid Droplet Formation inContact (Thousand Oaks (Ventura County, Calif.))Article
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Authors and funding
2 authors at 2 institutions in 2 countries.
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Abstract
Lipid droplets (LDs) are cellular compartments dedicated to the storage of metabolic energy in the form of neutral lipids, commonly known as "fat". The biogenesis of LDs takes place in the endoplasmic reticulum (ER), but its spatial and temporal organization is poorly understood. How exactly sites of LD formation are selected and the succession of proteins and lipids needed to mediate this process remains to be defined. In our current study we show that the yeast triacylglycerol (TAG)-synthases, Lro1 and Dga1 get recruited to discrete ER subdomains where they initiate TAG synthesis and hence LD formation (Choudhary
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.