Evidence map›Paper›PMID 32742992›Full record

ArticleWorld journal of clinical cases2020

Acute myelomonocytic leukemia during pembrolizumab treatment for non-small cell lung cancer: A case report.

Hong-Beum Kim, Sang-Gon Park, Ran Hong, Seong-Ho Kang, Yong Sub Na

Open access · diamondAbstract readCase Reports
In one paragraph

Article in World journal of clinical cases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Hong-Beum KimDepartment of Premedical Course, Chosun University School of Medicine, Gwangju 61452, South Korea.
Sang-Gon ParkDepartment of Hemato-oncology, Chosun University Hospital, Gwangju 61453, South Korea.
Ran HongDepartment of Pathology, Chosun University Hospital, Gwangju 61453, South Korea.
Seong-Ho KangDepartment of Laboratory Medicine, Chosun University Hospital, Gwangju 61453, South Korea.
Yong Sub NaDepartment of Pulmonology and Critical Care Medicine, Chosun University Hospital, Gwangju 61453, South Korea. ebusters@chosun.ac.kr.
Chosun University Hospital · KRChosun University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPembrolizumab is a highly selective IgG4 kappa isotype monoclonal antibody against the programmed cell death-1 (PD-1) molecule. In the treatment of non-small cell lung cancer (NSCLC), pembrolizumab has demonstrated significant efficacy, significant survival outcomes, long-lasting responses, and a good safety profile compared with cytotoxic chemotherapy. CASE SUMMARY: A 79-year-old Korean male presented with a left side palpable neck mass. An ultrasound-guided core-needle biopsy of the largest neck mass was performed, and squamous cell carcinoma was confirmed based on the histological and immunohistochemical findings. He was diagnosed with squamous cell carcinoma of the lung with multiple lymph nodes and rib metastases (T1N3M1b, Stage IVA) using enhanced chest computed tomography and

conclusionWe present the first report of acute myelomonocytic leukemia during pembrolizumab treatment in an NSCLC patient; the mechanism remains unknown.

Indexed as

Acute myeloid leukemiaAdverse eventsCase reportImmunotherapyNon-small cell lung cancer

Identifiers

PMID32742992
PMCPMC7360697
OpenAlexW3039766518

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.