Evidence map›Paper›PMID 32742920›Full record

ReviewIntegrative medicine research2020

Could herbal medicine (Soshihotang) be a new treatment option for COVID-19?: a narrative review.

Seungwon Kwon, Wonhaeng Lee, Chul Jin, Insoo Jang, Woo-Sang Jung, Sang-Kwan Moon, Ki-Ho Cho

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Integrative medicine research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Seungwon KwonDepartment of Cardiology and Neurology, College of Korean Medicine, Kyung Hee University, Seoul, South Korea.
Wonhaeng LeeLeewonhaeng-Whajubmong Korean Medicine Clinic, Goyang, South Korea.
Chul JinDepartment of Korean Medicine Cardiology and Neurology, Graduate School, Kyung Hee University, Seoul, South Korea.
Insoo JangDepartment of Internal Medicine, College of Korean Medicine, Woosuk University, Jeonju, South Korea.
Woo-Sang JungDepartment of Cardiology and Neurology, College of Korean Medicine, Kyung Hee University, Seoul, South Korea.
Sang-Kwan MoonDepartment of Cardiology and Neurology, College of Korean Medicine, Kyung Hee University, Seoul, South Korea.
Ki-Ho ChoDepartment of Cardiology and Neurology, College of Korean Medicine, Kyung Hee University, Seoul, South Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWhile the world struggles under the coronavirus disease 2019 (COVID-19) pandemic, a variety of antiviral agents and symptomatic treatments are being administered to patients and urgent clinical trials are underway. Under these circumstances, it is important to explore various possibilities for the treatment of COVID-19 including herbal medicines. Among various herbal medicines, Soshihotang (SSHT,

methodsFor conducting the present review, we searched electronic databases focusing on the antiviral effect of SSHT in experimental and clinical study until April 2020. The search keywords included SSHT, constituents of SSHT, and antiviral effect. We also searched for materials related to topic directly from websites and published books. Based on these search results, we summarized the results of the included materials in the form of a narrative review.

resultsIn a number of recent clinical studies, treatment with SSHT improved the infection status of the respiratory and hepatobiliary systems, and experimental studies demonstrated the antiviral effect of SSHT and its components. Furthermore, SSHT are being used in China-where COVID-19 outbreak first took place-and offer a new option to treat COVID-19.

conclusionBased on the present evidences, it is believed that SSHT is likely to be a new therapeutic option for COVID-19. Conducting further studies might provide improved understanding regarding the use of SSHT in treating COVID-19.

Indexed as

COVID-19Herbal medicineShosaikotoSoshihotangXiao Chai Hu Tang

Identifiers

PMID32742920
PMCPMC7366961

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.