Evidence map›Paper›PMID 32742861›Full record

ReviewCureus2020

Monoclonal Antibodies Addressed to Factors of Signalization in Keloid Scars: Opportunities and Areas of Action.

Erick Moreno Pizarro, Eduardo Morales Valencia, Arturo Pérez Cuéllar, Camilo Acuña Pinzon, Aarón Emanuel Serrano Padilla

Open access · diamondAbstract readReview
In one paragraph

Review in Cureus, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 90% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Erick Moreno PizarroMedicine, University of Guanajuato, León, MEX.
Eduardo Morales ValenciaSurgery, Hospital Regional de Alta Especialidad del Bajío, León, MEX.
Arturo Pérez CuéllarOrthopedics and Traumatology, General Hospital of León, León, MEX.
Camilo Acuña PinzonGeneral Surgery, Hospital Regional de Alta Especialidad del Bajío, León, MEX.
Aarón Emanuel Serrano PadillaMedicine, University of Guanajuato, León, MEX.
Hospital de León · ESHospital Regional de Alta Especialidad del Bajío · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The advance of technology has made possible the use of new techniques within medicine for the treatment of diseases; monoclonal antibodies are a clear example of this. Keloid scars are one of the most difficult pathologies to treat due to the high percentage of recidivism, formed by the growth of a scar with benign fibrous tissue in genetically predisposed individuals, resulting from a process of inflammation and abnormal scarring. Monoclonal antibodies, being a line of treatment that has increased over the years, can show a new frontier in the treatment of them by focusing on the signaling that causes it. We review the literature on the signaling mechanisms of keloid scars and the possible monoclonal approach.

Indexed as

abnormal scarringaestheticgeneticskeloid scarmonoclonal antibodiesscar appearance

Identifiers

PMID32742861
PMCPMC7389189
OpenAlexW3037921994

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.