Evidence map›Paper›PMID 32742792›Full record

ArticlePeerJ2020

Chlorine-based DUWL disinfectant leads to a different microbial composition of water derived biofilms compared to H

Charifa Zemouri, Alexa M G A Laheij, Catherine M C Volgenant, Bernd W Brandt, Wim Crielaard, Mark J Buijs, Egija Zaura, Johannes J de Soet

Abstract read
In one paragraph

Article in PeerJ, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Charifa ZemouriDepartment of Preventive Dentistry, Academic Centre for Dentistry Amsterdam, Amsterdam, The Netherlands.
Alexa M G A LaheijDepartment of Preventive Dentistry, Academic Centre for Dentistry Amsterdam, Amsterdam, The Netherlands.
Catherine M C VolgenantDepartment of Preventive Dentistry, Academic Centre for Dentistry Amsterdam, Amsterdam, The Netherlands.
Bernd W BrandtDepartment of Preventive Dentistry, Academic Centre for Dentistry Amsterdam, Amsterdam, The Netherlands.
Wim CrielaardDepartment of Preventive Dentistry, Academic Centre for Dentistry Amsterdam, Amsterdam, The Netherlands.
Mark J BuijsDepartment of Preventive Dentistry, Academic Centre for Dentistry Amsterdam, Amsterdam, The Netherlands.
Egija ZauraDepartment of Preventive Dentistry, Academic Centre for Dentistry Amsterdam, Amsterdam, The Netherlands.
Johannes J de SoetDepartment of Preventive Dentistry, Academic Centre for Dentistry Amsterdam, Amsterdam, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBiofilm formation in dental unit waterlines (DUWL) may lead to health risks for dental staff and patients. Therefore, dental unit waterlines need to be disinfected, for instance by using chemical disinfectants. However, the application of chemical disinfectants may lead to the selection of specific microorganisms. Therefore, the aim of our study was to assess the microbial composition of water-derived biofilms, after a continuous exposure to maintenance doses of commercially available chemical disinfectants, in vitro.

methodsThe AAA-model was used to grow water derived biofilms. The biofilms were subjected to the maintenance dose of each disinfectant. To determine the microbial composition, the V4 hypervariable region of the 16S rRNA gene was sequenced. The sequences were clustered in operational taxonomic units (OTUs).

resultsThe bacterial composition of biofilms in all treatment groups differed significantly (PERMANOVA

conclusionWe concluded that exposure to low doses of the chlorine-based chemical disinfectant Anoxyl led to a substantially different composition of water derived biofilms compared to biofilms exposed to H

Indexed as

BiofilmDental unit waterlinesDisinfectionMicrobiomeSequencingWater quality

Identifiers

PMID32742792
PMCPMC7368430

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.