Evidence map›Paper›PMID 32742671›Full record

ArticleGlobal mental health (Cambridge, England)2020

Caregiving burden and mental health problems among family caregivers of people with dementia in rural Uganda.

Herbert E Ainamani, Paul E Alele, Godfrey Z Rukundo, Samuel Maling, Edith K Wakida, Celestino Obua, Alexander C Tsai

Open access · goldAbstract read
In one paragraph

Article in Global mental health (Cambridge, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
7.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Dementia knowledge and caregiver burden among carers of older adults in rural eastern Uganda.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Herbert E AinamaniMbarara University of Science and Technology, Mbarara, Uganda.ORCID https://orcid.org/0000-0001-7290-7232
Paul E AleleMbarara University of Science and Technology, Mbarara, Uganda.
Godfrey Z RukundoMbarara University of Science and Technology, Mbarara, Uganda.
Samuel MalingMbarara University of Science and Technology, Mbarara, Uganda.
Edith K WakidaMbarara University of Science and Technology, Mbarara, Uganda.
Celestino ObuaMbarara University of Science and Technology, Mbarara, Uganda.
Alexander C TsaiMbarara University of Science and Technology, Mbarara, Uganda.
Mbarara University of Science and Technology · UGHarvard University · US

Funding

Mbarara University Research Training Initiative (MURTI)D43TW010128 · FIC · MBARARA UNIVERSITY/SCIENCE/ TECHNOLOGY · PI OBUA, CELESTINO · 2015 to 2019
$3.5M
Social Networks, HIV Stigma, and the HIV Care Cascade in Rural UgandaR01MH113494 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI TSAI, ALEXANDER C · 2017 to 2021
$3.2M
FIC NIH HHS D43 TW010128NIMH NIH HHS R01 MH113494
6 · The paper itself

Abstract

backgroundAlzheimer's disease and related dementias are associated with increasing health burden in low- and middle-income countries. Less well-recognized is the potential health burden experienced by other affected individuals, such as family caregivers. In this study, we sought to profile the burden of care and its association with symptoms of depression and anxiety among informal caregivers of people living with dementia in rural southwestern Uganda.

methodWe conducted a cross-sectional study of 232 family caregivers of people with dementia. The key measured variables of interest were caregiving burden (Zarit Burden Index) and symptoms of depression and anxiety (Depression Anxiety Stress Scales). We fitted multivariable regression models specifying depression and anxiety symptoms as the primary outcomes of interest and caregiving burden as the primary explanatory variable of interest.

resultsFamily caregivers of people with dementia experience significant caregiving burden, with each item on the Zarit Burden Index endorsed by more than 70% of study participants. Nearly half [108 (47%)] of caregivers had Zarit Burden Interview scores >60, suggestive of severe caregiving burden. In multivariable regression models, we estimated a statistically significant positive association between caregiving burden and symptoms of both depression [

conclusionFamily caregivers of people with dementia in rural Uganda experience a high caregiving burden, which is associated with symptoms of depression and anxiety. Interventions aimed at reducing caregiving burden may have important collateral mental health benefits.

Indexed as

Alzheimer's diseaseanxietycaregiving burdendementiadepressionsub-Saharan AfricaUganda

Identifiers

PMID32742671
PMCPMC7379317
OpenAlexW3029859320

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.