ArticleExperimental and therapeutic medicine2020
Ossification of the ligamentum flavum in the upper cervical spine: A report of two cases and literature review.
Article in Experimental and therapeutic medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
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Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.
- Cervical Ossification of Ligamentum Flavum: Elaborating an Underappreciated but Occasional Contributor to Myeloradiculopathy in Aging Population Based on Synthesis of Individual Participant Data.Clinical interventions in aging · 2021Pooled it
- Cervical Myelopathy Caused by Ossification of the Posterior Atlantoaxial Membrane and Heterotopic Ossification between the Posterior Arches of the Atlas and Axis: A Case Report.Spine surgery and related research · 2026Article
- Thoracic Myelopathy in Ossified Ligamentum Flavum: Surgical Management and Long-Term Outcome Following 2 Different Techniques of Surgical Decompression.Global spine journal · 2023Article
- Effects of cervical rotatory manipulation on the cervical spinal cord: a finite element study.Journal of orthopaedic surgery and research · 2021Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ossification of the ligamentum flavum (OLF) is rarely observed in the cervical spine, particularly not in the upper cervical spine. The present report describes two cases of OLF combined with cervical myelopathy and provides a literature review with a comparative analysis of previous studies and the present cases. Pre-operative CT, MRI and histological examination were performed to confirm the diagnosis of these patients (A 37-year-old female and 63-year-old male). In both cases, histological examination of surgical specimens revealed OLF. The symptoms of the two patients significantly improved after surgery and no recurrence was observed at 13 months after surgery. Furthermore, the clinical outcomes were satisfactory and the internal fixation was solid in the two cases. Review of the literature suggested that further research is required to reveal the optimal treatment methods for upper cervical OLF.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.