ArticleSaudi journal of biological sciences2020
Hydroxyapatite based biocomposite scaffold: A highly biocompatible material for bone regeneration.
Article in Saudi journal of biological sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Towards MRI Study of Biointegration of Carbon-Carbon Composites with Ca-P Coatings.Nanomaterials (Basel, Switzerland) · 2025Article
- Efficacy of a gelatin-based hemostatic sponge and hydroxyapatite-chitosan nanocomposites (nHAp/CS) on regeneration of radial bone defects in rabbits.Open veterinary journal · 2025Article
- Chitin scaffolds derived from the marine demospongeFrontiers in bioengineering and biotechnology · 2023Article
- Current Development in Biomaterials-Hydroxyapatite and Bioglass for Applications in Biomedical Field: A Review.Journal of functional biomaterials · 2022Review
- Strontium-incorporated bioceramic scaffolds for enhanced osteoporosis bone regeneration.Bone research · 2022Article
- Investigations on the Influence of Collagen Type on Physicochemical Properties of PVP/PVA Composites Enriched with Hydroxyapatite Developed for Biomedical Applications.Materials (Basel, Switzerland) · 2021Article
- Recycled Porcine Bone Powder as Filler in Thermoplastic Composite Materials Enriched with Chitosan for a Bone Scaffold Application.Polymers · 2021Article
- Ursolic Acid Loaded-Mesoporous Hydroxylapatite/ Chitosan Therapeutic Scaffolds Regulate Bone Regeneration Ability by Promoting the M2-Type Polarization of Macrophages.International journal of nanomedicine · 2021Article
Corrections and comments
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Authors and funding
6 authors.
Funding
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Abstract
The conventional approaches for treating bone defects such as autografts donor tissue shortages and allografts transmission of diseases pose many shortcomings. The objective of this study was to design a nano strontium/magnesium doped hydroxyapatite (Sr/Mg-HA) with chitosan (CTS) and multi-walled carbon nanotubes (MWCNT) (Sr/Mg-HA/MWCNT/CTS) biocomposite was created to support the growth of osteoblasts using a solvent evaporation method. To help the growth of osteoblasts, a solvent evaporation technique was used to design a nano strontium/magnesium doped hydroxyapatite with chitosan and multi-walled carbon nanotubes biocomposite. We studied the biocompatibility and efficiency in vitro of biocomposite following physicochemical analyzes. Tests of biocompatibility, cell proliferation, mineralization, and osteogenic differentiation have shown that in-vitro safety and effectiveness of biocomposite are good. The performance of biocomposite was more efficient in in-vitro as well as in vivo experiments than in Sr/Mg-HA nanoparticles. Briefly, the Sr/Mg-HA/MWCNT/CTS biocomposite is an ideal candidate for effective bone repair in clinics with excellent mechanical properties with durable multi-biofunctional antibacterial properties and osteoinductivity.
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