Tuberculosis treatment outcome in Thessaloniki, Greece - a single center study.

K Manika, S C Kotoulas, E Papadaki, P Kyreltsi, M Sionidou, T Kontakiotis, I Kioumis

Abstract read

In one paragraph

Article in Hippokratia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Bone and Joint Tuberculosis in Greece: A Retrospective Study From 2011 to 2019.Cureus · 2022
Article

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

K ManikaPulmonary Department, Medical School, Aristotle University of Thessaloniki, "G. Papanikolaou" Hospital, Thessaloniki, Greece.

S C KotoulasPulmonary Department, Medical School, Aristotle University of Thessaloniki, "G. Papanikolaou" Hospital, Thessaloniki, Greece.

E PapadakiPulmonary Department, Medical School, Aristotle University of Thessaloniki, "G. Papanikolaou" Hospital, Thessaloniki, Greece.

P KyreltsiPulmonary Department, Medical School, Aristotle University of Thessaloniki, "G. Papanikolaou" Hospital, Thessaloniki, Greece.

M SionidouPulmonary Department, Medical School, Aristotle University of Thessaloniki, "G. Papanikolaou" Hospital, Thessaloniki, Greece.

T KontakiotisPulmonary Department, Medical School, Aristotle University of Thessaloniki, "G. Papanikolaou" Hospital, Thessaloniki, Greece.

I KioumisRespiratory Failure Department, Medical School, Aristotle University of Thessaloniki, "G. Papanikolaou" Hospital, Thessaloniki, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGreece is one of the few countries in the European Union/European Economic Area, which do not report tuberculosis (TB) treatment outcome. This study aimed to assess treatment outcomes and identify possible intervening factors in patients with TB in Thessaloniki, Greece, over the period 2012-2017.

methodsAll patients diagnosed with TB -excluding rifampicin-resistant/multidrug-resistant (RR/MDR)-TB- during 2015-2017 were included in the study. Data on demographic characteristics, localization, diagnostic methods, resistance, and treatment outcome were recorded and compared to the period 2012-2014.

resultsDuring the period 2015-2017, 82 patients (48 men) with a mean age of 53.8 ± 15.6 years were diagnosed with TB. No significant differences in demographics, microbiological, or treatment characteristics were detected between the two three-year periods, except for the percentage of immunocompromised patients, which was higher during 2015-2017 (15.9 % vs 5.6 %, p =0.029). In the total number of patients, two factors were significantly different between patients with a positive and negative outcome. The percentage of favorable outcome was higher for patients with extrapulmonary compared to pulmonary TB (90.9 % vs 70.5 %, p =0.044). Furthermore, the percentage of immunocompetent patients with a positive outcome was significantly higher in the second treatment period compared to the first (treatment success rate 66.7 % in 2012-2014 vs 84.1 % in 2015-2017, p =0.014). This difference was attributed to the presence of a social nurse who joined the center in 2015.

conclusionsTB treatment success rate in Greece is below the World Health Organization standards. Interventions such as appropriate multidisciplinary staffing of TB centers may prove valuable in improving TB care in Greece. HIPPOKRATIA 2019, 23(4): 154-159.

Indexed as

Greeceoutcometreatment success rateTuberculosis

Identifiers

PMID32742164

PMCPMC7377584

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.