ArticleWorld journal of gastroenterology2020
Functionality is not an independent prognostic factor for pancreatic neuroendocrine tumors.
Article in World journal of gastroenterology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 7 citations in OpenAlex.
- The incidence, prevalence, and survival analysis of pancreatic neuroendocrine tumors in the United States.Journal of endocrinological investigation · 2023Article
- Development and validation of a survival prediction model and risk stratification for pancreatic neuroendocrine neoplasms.Journal of endocrinological investigation · 2023Article
- Identifying target ion channel-related genes to construct a diagnosis model for insulinoma.Frontiers in genetics · 2023Article
- Gender differences in pancreatic neuroendocrine neoplasms: A retrospective study based on the population of Hubei Province, China.Frontiers in endocrinology · 2022Article
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPancreatic neuroendocrine neoplasms (pNENs) that produce hormones leading to symptoms are classified as functional tumors, while others are classified as nonfunctional tumors. The traditional view is that functionality is a factor that affects the prognosis of pNEN patients. However, as the sample sizes of studies have increased, researches in recent years have proposed new viewpoints.
aimTo assess whether functionality is an independent factor for predicting the prognosis of pNEN patients.
methodsFrom January 2004 to December 2016, data of patients who underwent surgery at the primary site for the treatment of pNENs from the Surveillance, Epidemiology, and End Results (SEER) database and West China Hospital database were retrospectively analyzed.
resultsContemporaneous data from the two databases were analyzed separately as two cohorts and then merged as the third cohort to create a large sample that was suitable for multivariate analysis. From the SEER database, age (
conclusionFunctionality is not associated with prognosis. Race, age, sex, and T stage are independent factors for predicting the survival of patients with pNETs.
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