Resolution of neurologic signs presumed to be associated with hyperammonemia in 2 endurance horses.

C Langdon Fielding, K Gary Magdesian, Jennifer R Mayer

Open access · greenAbstract readCase Reports

In one paragraph

Article in The Canadian veterinary journal = La revue veterinaire canadienne, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact, top 91% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

C Langdon FieldingLoomis Basin Equine Medical Center, 2973 Penryn Road, Penryn, California 95663, USA (Fielding, Mayer); Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, 1 Garrod Drive, Davis, California 95616, USA (Magdesian).

K Gary MagdesianLoomis Basin Equine Medical Center, 2973 Penryn Road, Penryn, California 95663, USA (Fielding, Mayer); Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, 1 Garrod Drive, Davis, California 95616, USA (Magdesian).

Jennifer R MayerLoomis Basin Equine Medical Center, 2973 Penryn Road, Penryn, California 95663, USA (Fielding, Mayer); Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, 1 Garrod Drive, Davis, California 95616, USA (Magdesian).

University of California, Davis · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This case report describes 2 endurance horses with non-hepatic hyperammonemia. The animals were competing in a 160-km endurance competition in extreme heat conditions and were presented for obtundation. One of the horses also had evidence of blindness. The blood ammonia concentration was elevated (196 μmol/L and 249 μmol/L) and both horses improved following treatment with intravenous fluids and supportive care. These are the first documented cases of clinical signs presumed to be associated with hyperammonemia in endurance horses. Despite the severity of the clinical presentation, both horses made a full recovery. Key clinical message: Non-hepatic hyperammonemia should be considered as a potential cause of blindness and obtundation in competing endurance horses. Horses appear to respond well to treatment with intravenous fluids.

Indexed as

Horse DiseasesHyperammonemiaPhysical Conditioning, AnimalAnimalsHorses

Identifiers

PMID32741992

PMCPMC7350152

OpenAlexW3047777025

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.