Evidence map›Paper›PMID 32741842›Full record

ArticleJournal of Parkinson's disease2020

Hallucinations and Development of Dementia in Parkinson's Disease.

Wojciech Gryc, Kathryn A Roberts, Cyrus P Zabetian, Daniel Weintraub, John Q Trojanowski, Joseph F Quinn, Amie L Hiller, Kathryn A Chung, Kathleen L Poston, Laurice Yang and 4 more

Registry-linked trialOpen access · greenAbstract readLetter
In one paragraph

Article in Journal of Parkinson's disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01720810 (Pacific Northwest Udall Center), which is not on this map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
0.6field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01720810 unknown statusnot on this map

Pacific Northwest Udall Center (PANUC) Clinical Core

TypeobservationalSponsorUniversity of WashingtonRan2010 to 2025Enrolled2,000ConditionsParkinson Disease, Cognitive Impairment
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 19 citations in OpenAlex.

  1. The prevalence of apathy in Lewy body dementia: A systematic review and meta-analysis.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Review
  6. Combined Dysfunction of the Amygdala and Nucleus Basalis Underlies Visual Hallucinations in Parkinson's Disease.Movement disorders : official journal of the Movement Disorder Society · 2025
    Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 9 institutions in 1 country.

Wojciech GrycVeterans Affairs Puget Sound Health Care System, Seattle, WA, USA.
Kathryn A RobertsVeterans Affairs Puget Sound Health Care System, Seattle, WA, USA.
Cyrus P ZabetianVeterans Affairs Puget Sound Health Care System, Seattle, WA, USA.
Daniel WeintraubDepartment of Neurology, University of Pennsylvania, Philadelphia, PA, USA.
John Q TrojanowskiDepartment of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Joseph F QuinnPortland Veterans Affairs Medical Center, Portland, OR, USA.
Amie L HillerPortland Veterans Affairs Medical Center, Portland, OR, USA.
Kathryn A ChungPortland Veterans Affairs Medical Center, Portland, OR, USA.
Kathleen L PostonDepartment of Neurology and Neurological Sciences, Stanford School of Medicine, Palo Alto, CA, USA.
Laurice YangDepartment of Neurology and Neurological Sciences, Stanford School of Medicine, Palo Alto, CA, USA.
Shu-Ching HuVeterans Affairs Puget Sound Health Care System, Seattle, WA, USA.
Karen L EdwardsDepartment of Epidemiology, University of California, Irvine, School of Medicine, Irvine, CA, USA.
Thomas J MontineDepartment of Pathology, Stanford University School of Medicine, Palo Alto, CA, USA.
Brenna A CholertonDepartment of Pathology, Stanford University School of Medicine, Palo Alto, CA, USA.
Portland VA Medical Center · USStanford Medicine · USStanford University · USUniversity of Washington · USVA Puget Sound Health Care System · USOregon Health & Science University · USUniversity of California, Irvine · USUniversity of Pennsylvania · USVeterans Health Administration · US

Funding

Project IV: "Alpha-Synuclein Strains & Diverse Synucleinopathies"P50NS053488 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI TROJANOWSKI, JOHN Q. · 2007 to 2017
$20.9M
Udall Center Director's meeting poster awardP50NS062684 · NINDS · UNIVERSITY OF WASHINGTON · PI MONTINE, THOMAS J · 2009 to 2020
$18.3M
Project IV "Tackling Heterogeneity of Cognitive Trajectory in LBD"U19AG062418 · NIA · UNIVERSITY OF PENNSYLVANIA · PI TROJANOWSKI, JOHN Q. · 2019 to 2023
$18.1M
Genetic Movement Disorders: Etiologies and PathogenesesI01CX001702 · VA · VA PUGET SOUND HEALTHCARE SYSTEM · PI CYRUS P ZABETIAN · 2018 to 2026
–
CSRD VA I01 CX001702NIA NIH HHS U19 AG062418NINDS NIH HHS P50 NS053488NINDS NIH HHS P50 NS062684
6 · The paper itself

Abstract

Neuropsychiatric symptoms are common in Parkinson's disease (PD). We investigated the relationship between neuropsychiatric symptoms and current and future diagnosis of PD dementia (PDD). Individuals with PD who had a study partner were enrolled (n = 696). Study partners were administered the Neuropsychiatric Inventory or Neuropsychiatric Inventory Questionnaire at baseline. Participants were assigned a cognitive diagnosis at baseline and follow up visits. Hallucinations were significantly associated with a diagnosis of PDD cross-sectionally (p < 0.001) and with shortened time to dementia longitudinally among initially nondemented participants (n = 444; p = 0.005). Screening for hallucinations may be useful for assessing risk of dementia in participants with PD.

Indexed as

AgedBehavioral SymptomsCognitive DysfunctionCross-Sectional StudiesDementiaFemaleHallucinationsHumansLongitudinal StudiesMaleMiddle AgedParkinson DiseaseBehavioral symptomscognitiondementiahallucinationsParkinson’s disease

Identifiers

PMID32741842
PMCPMC7609584
OpenAlexW3046451223

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.