ArticleJournal of substance abuse treatment2020
Something to despair: Gender differences in adverse childhood experiences among rural patients.
Article in Journal of substance abuse treatment, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 39 citations in OpenAlex.
- The Role of Child Maltreatment and Revictimization on Substance Use Trajectories Among Women Involved in the Criminal Justice System.Women & criminal justice · 2025Article
- Adverse childhood experiences and preventive health care among rural US children: A cross-sectional examination of 2022 National Health Interview Survey data.The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association · 2025Article
- The Impact of Adverse Childhood Experiences on Asthma Severity in US Adults.Medical sciences (Basel, Switzerland) · 2024Article
- Internalizing Pathways to Adolescent Substance Use from Adverse Childhood Experiences.International journal of environmental research and public health · 2024Article
- Early vs. Later Experiences of Violence and Polysubstance Use Among Adults Who Inject Drugs.Substance use & misuse · 2024Article
- Announcing the Alliance against Violence and Adversity (AVA): a new Canadian Institutes of Health Research Training Platform.Canadian journal of public health = Revue canadienne de sante publique · 2023Article
- Sex Differences in Patterns of Childhood Traumatic Experiences in Chinese Rural-To-Urban Migrant Children.Children (Basel, Switzerland) · 2023Article
- Consideration of sex and gender in Alzheimer's disease and related disorders from a global perspective.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2022Article
- Association of co-occurring mental health problems with hepatitis C status among young people who inject drugs in rural New Mexico, 2016-2018.Addiction science & clinical practice · 2022Article
- Sex differences in the association of adverse childhood experiences on past 30-day opioid misuse among Florida justice-involved children.Journal of substance abuse treatment · 2022Article
- Regional prevalence of adverse childhood experiences in the United States using a nationally representative school-based sample.SSM - population health · 2022Article
- Adverse childhood experiences among females in substance use treatment and their children: A pilot study.Preventive medicine reports · 2021Article
- Early Life Stress and Risks for Opioid Misuse: Review of Data Supporting Neurobiological Underpinnings.Journal of personalized medicine · 2021Review
- Feasibility and acceptability of safety screening among patients receiving addiction treatment.Journal of substance abuse treatment · 2020Article
- Effects of Early Life Trauma on Risks for Adult Opioid Use Disorder Are Mediated by Stress and Occur Independent of Depression and Anxiety.Journal of addiction medicineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
Existing research has demonstrated that patients in treatment for an opioid use disorder (OUD) have high rates of adverse childhood experiences (ACE) compared to community-based samples. While research has documented important gender differences in ACEs in patients with OUD receiving treatment in urban areas, research has not shown whether these findings would generalize to rural and Appalachian areas, which are known to have lower ACE scores. We conducted a secondary analysis of existing clinical data, utilizing intake assessment data from a rural Appalachian outpatient buprenorphine program. We restricted the sample to patients with an OUD who presented for treatment between June 2018 and June 2019 (n = 173). The clinical intake assessment included a modified 17-item ACE instrument that patients self-administered. More than half (54.3%) of patients reported having experienced 4+ categories of adverse childhood experiences. On average, females endorsed 4.5 categories of adverse experiences, whereas males endorsed 3.3 (p < 0.00); female patients were significantly more likely to have experienced sexual abuse (42.4% versus 10.6%, p < 0.00). Alarmingly, 25.9% of females and 8.2% of males reported being forced to have sex before age 18. Disproportionately high rates of childhood adversities, particularly among females, may partially explain despair in rural Appalachian areas. OUD treatment programs should conduct clinical assessments of trauma and integrate trauma-informed care into drug treatment, especially for female patients residing in rural Appalachia.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.