Evidence map›Paper›PMID 32741411›Full record

ArticleParasitology2020

Chemical characterization and

Letícia Oliveira da Rocha, Gloria Cristina da Silva Lemos, Ivo José Curcino Vieira, Raimundo Braz-Filho, Silvério de Paiva Freitas, Leonardo Siqueira Glória, Clóvis de Paula Santos

Abstract read
In one paragraph

Article in Parasitology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Ocimum micranthum essential oil as a sustainable phytotherapeutic alternative against Haemonchus contortus.Revista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinaria · 2026
    Article
  2. Article
  3. Cymbopogon citratus showing nematicidal activity against Heligmosomoides polygyrus bakeri.Revista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinaria · 2024
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Letícia Oliveira da RochaLaboratório de Biologia Celular e Tecidual, Centro de Biociências e Biotecnologia, Universidade Estadual do Norte Fluminense Darcy Ribeiro, Av. Alberto Lamego, 2000, Parque Califórnia, Campos dos Goytacazes, RJ28013-602, Brazil.
Gloria Cristina da Silva LemosLaboratório de Fitotecnia, Centro de Ciências Tecnológicas e Agropecuárias, Universidade Estadual do Norte Fluminense, Av. Alberto Lamego, 2000, Parque Califórnia, Campos dos Goytacazes, RJ, 28013-602, Brazil.
Ivo José Curcino VieiraLaboratório de Ciências Químicas, Centro de Ciências Tecnológicas, Universidade Estadual do Norte Fluminense, Av. Alberto Lamego, 2000, Parque Califórnia, Campos dos Goytacazes, RJ, 28013-602, Brazil.
Raimundo Braz-FilhoPesquisador Emérito-FAPERJ, DQO-IQ - Universidade Federal Rural do Rio de Janeiro (UFRRJ)/LCQUI - CCT - Universidade Estadual do Norte Fluminense Darcy Ribeiro (UENF) Rodovia BR 465, Km 07, s/n Zona Rural, Seropédica - RJ, 23890-000 Brazil e Av. Alberto Lamego, 2000, Parque Califórnia, Campos dos Goytacazes, RJ, 28013-602, Brazil.
Silvério de Paiva FreitasLaboratório de Fitotecnia, Centro de Ciências Tecnológicas e Agropecuárias, Universidade Estadual do Norte Fluminense, Av. Alberto Lamego, 2000, Parque Califórnia, Campos dos Goytacazes, RJ, 28013-602, Brazil.
Leonardo Siqueira GlóriaLaboratório de Zootecnia, Centro de Ciências Tecnológicas e Agropecuárias, Universidade Estadual do Norte Fluminense, Av. Alberto Lamego, 2000, Parque Califórnia, Campos dos Goytacazes, RJ, 28013-602, Brazil.
Clóvis de Paula SantosLaboratório de Biologia Celular e Tecidual, Centro de Biociências e Biotecnologia, Universidade Estadual do Norte Fluminense Darcy Ribeiro, Av. Alberto Lamego, 2000, Parque Califórnia, Campos dos Goytacazes, RJ28013-602, Brazil.ORCID 0000-0003-1416-288X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Medicinal plants have been the focus of several studies due to their nematicide properties which can be used to control nematodes in sheep. No study has examined the morphological effects of Cymbopogon citratus on nematodes. Thus, this study evaluated the chemical composition, nematicidal activity and effects of C. citratus extracts on the morphology of eggs and infective larvae (L3) of sheep. Aqueous and methanolic extracts and fractions of C. citratus were obtained and analysed in vitro. The C. citratus extracts were effective against Haemonchus spp. and Trichostrongylus spp. larvae and eggs. Ten fractions were obtained from C. citratus, six of which had high ovicidal activity at 1000 μg mL-1, and two fractions had high activity at all tested concentrations. The phytochemical analysis identified the presence of compounds such as terpenoids, various ketones, esters, and fatty acids. The ultrastructural analysis showed deformations of the cuticle and wilting along the body of the nematodes at all concentrations. The muscular layer, intestinal cells and the mitochondria profile showed damage compared to the typical pattern. Ultra-thin sections of eggs treated with methanolic fractions of C. citratus presented modifications. This study showed the biological activity and effects of C. citratus on the gastrointestinal nematodes in sheep.

Indexed as

AnimalsBrazilCymbopogonHaemonchiasisHaemonchusLarvaOvumPlant ExtractsPlants, MedicinalSheepSheep DiseasesSheep, DomesticTrichostrongylosisTrichostrongylusPlant ExtractsCymbopogon citratusgastrointestinal nematodessheepsmall ruminants

Identifiers

PMID32741411
PMCPMC10317736

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.